unyango unyango umhlaza wemiphunga entsha

Ukuhamba kuNyango olutsha loMhlaza weMiphunga: Isikhokelo esiBanzi

Esi sikhokelo sinika amagqabantshintshi ngoku kunye nokuvelayo unyango unyango umhlaza wemiphunga entsha iinketho, kugxilwe kwinkqubela phambili kunye nokuqwalaselwa kwezigulane. Siphonononga iindlela ezahlukeneyo zonyango, ukusebenza kwazo, iziphumo ebezingalindelekanga ezinokubakhona, kunye nokubaluleka kwezicwangciso zonyango lomntu ngamnye. Funda ngophando lwamva nje kunye nendlela yokwenza izigqibo ezinolwazi ngentsebenziswano neqela lakho lezempilo.

Ukuqonda uMhlaza wemiphunga kunye neentlobo zayo

Umhlaza wamaphaphu sisifo esintsonkothileyo esineentlobo ezahlukeneyo, nganye ifuna indlela elungiselelweyo unyango unyango umhlaza wemiphunga entsha. Umhlaza wemiphunga yeseli encinci (SCLC) kunye nomhlaza wemiphunga weseli ongeyonxalenye encinci (NSCLC) zezona ndidi zimbini ziphambili, kunye ne-NSCLC yahlulahlulwe ngakumbi ngokwee-subtypes ngokusekwe kutshintsho lwemfuza kunye nezinye iimpawu. Ukuxilongwa ngokuchanekileyo, kubandakanywa nesiteji, kubalulekile ekumiseleni isicwangciso sonyango esilungileyo.

Inqanaba kunye nokuxilongwa

Ukulinganisa kubandakanya ukujonga ubungakanani bokusasazeka komhlaza. Oku kwenziwa ngovavanyo lwemifanekiso efana neCT scans kunye nePET scans, kwakunye nebiopsies. Ukufunyanwa kwangoko kuphucula kakhulu iziphumo zonyango, kugxininisa ukubaluleka kokuhlolwa rhoqo, ngakumbi kubantu abasengozini enkulu. Uvavanyo lwemfuzo lukwabalulekile ekuchongeni iinguqulelo ezithile ezinokukhokela unyango unyango umhlaza wemiphunga entsha izigqibo.

UKhetho lwangoku loNyango loMhlaza omtsha weMiphunga

Ukhetho lonyango lomhlaza wemiphunga luqhubele phambili kakhulu kule minyaka yakutsha nje, lubonelela ngoluhlu olubanzi lweendlela eziphuculiweyo kunye neziphumo ebezingalindelekanga ezincitshisiweyo.

Utyando

Utyando lolona khetho luphambili kumhlaza wemiphunga wenqanaba lakwangoko. Ubuchwephesha obungenabuqhetseba obuncinci, obufana notyando lwethoracoscopic oluncediswa yividiyo (i-VATS), luhlala lukhethwa kumathumba amancinci, okukhokelela kwiinkqubo ezingaphantsi kunye namaxesha okubuyisela ngokukhawuleza. Indlela yotyando ethile ixhomekeke kubungakanani, indawo, kunye nenqanaba lethumba.

Unyango ngamachiza

I-Chemotherapy isebenzisa amayeza okubulala iiseli zomhlaza. Isetyenziswa rhoqo kunye nolunye unyango, olufana noqhaqho okanye unyango ngemitha. Kukho iirejimeni ezahlukeneyo zechemotherapy ezikhoyo, kwaye ukhetho luxhomekeke kuhlobo oluthile kunye nenqanaba lomhlaza wemiphunga. Iziphumo ebezingalindelekanga eziqhelekileyo ziquka ukudinwa, isicaphucaphu, nokulahleka kweenwele, kodwa ezi zihlala zilawuleka.

Unyango ngemitha

Unyango ngemitha lusebenzisa imitha yemitha ephezulu ukutshabalalisa iiseli zomhlaza. Ingasetyenziswa ngaphambi, ngexesha, okanye emva kotyando ukunciphisa amathumba, ukuthintela ukuphinda umhlaza, okanye ukuthomalalisa iimpawu. Iindidi ezahlukeneyo zonyango lwemitha zikhona, kubandakanywa unyango lwemitha yangaphandle kunye ne-brachytherapy (imitha yangaphakathi). Iindlela eziphucukileyo ezifana ne-stereotactic body radiotherapy (SBRT) zivumela ukujoliswa okuchanekileyo kwamathumba, ukunciphisa umonakalo kwizihlunu ezisempilweni ezingqongileyo.

Unyango ekujoliswe kulo

Unyango olujoliswe kuyo lujolise kwiimolekyuli ezithile ezibandakanyekayo ekukhuleni kweeseli zomhlaza. Ezi zonyango zilungiselelwe izigulane ezineenguqu ezithile zofuzo, ezifana ne-EGFR, ALK, kunye nokuguqulwa kwe-ROS1. Bahlala beneziphumo ebezingalindelekanga ezimbalwa xa kuthelekiswa nechemotherapy yesintu. Imizekelo ibandakanya i-EGFR tyrosine kinase inhibitors (TKIs) njengeGefitinib kunye ne-Erlotinib. Iziko loPhando ngoMhlaza laseShandong Baofa (https://www.baofahospital.com/) uphambili kuphando kunye nokusetyenziswa kwezi ziphambili unyango unyango umhlaza wemiphunga entsha iindlela.

Immunotherapy

I-Immunotherapy idibanisa amajoni omzimba ukulwa neeseli zomhlaza. Ii-Checkpoints inhibitors, ezifana ne-Pembrolizumab kunye ne-Nivolumab, zivimba iiprotheni ezithintela amajoni omzimba ekuhlaseleni iiseli zomhlaza. Olu nyango lubonise impumelelo ephawulekayo kwiintlobo ezithile zomhlaza wemiphunga. Imiphumo emibi inokwahluka, kwaye ukubeka iliso ngokusondeleyo kubalulekile.

Ukukhetha iSicwangciso soNyango esiLungileyo

Ukukhetha eyona ilungileyo unyango unyango umhlaza wemiphunga entsha isicwangciso sifuna uqwalaselo ngononophelo lwemiba eyahlukeneyo. Oku kuquka uhlobo kunye nenqanaba lomhlaza wemiphunga, impilo yesigulana iyonke, izinto esizikhethayo, kunye nokufumaneka konyango oluthile. Iqela lezinto ezininzi, kubandakanywa ii-oncologists, oogqirha botyando, i-radiation oncologists, kunye nezinye iingcali, zisebenza ngokubambisana ukuphuhlisa isicwangciso sonyango lomntu.

Uvavanyo lweklinikhi kunye noNyango olusakhulayo

Uphando luqhubeleka phambili ekuqondeni umhlaza wemiphunga kunye nokuphuhlisa iindlela ezintsha zonyango. Ukuthatha inxaxheba kwiimvavanyo zeklinikhi kunika ukufikelela kwiindlela ezintsha zonyango kunye negalelo ledatha ebalulekileyo yokuphucula iindlela zonyango ezizayo. Soloko uxoxa ngokuthatha inxaxheba kulingo lwezonyango kunye nomboneleli wakho wezempilo.

I-Disclaimer: Le ngcaciso yenzelwe iinjongo zemfundo kuphela kwaye akufanele ithathwe njengengcebiso yezonyango. Soloko ubonisana nengcali yezempilo ukuxilongwa kunye nonyango lwaso nasiphi na isimo sonyango.