unyango olungelulo oluncinci unyango lomhlaza wemiphunga kufutshane nam

Ukufumana iLungelo Unyango olungelulo Unyango loMhlaza weMiphuphu yeSeli encinci Kufuphi nam

Esi sikhokelo sibanzi sikunceda ukuba ukhangele ubunzima bokufumana okusebenzayo unyango olungelulo oluncinci lwe-cell lung cancer (NSCLC). iinketho ezikufutshane nawe. Siphonononga iindlela ezahlukeneyo zonyango, iingqwalasela zokukhetha ukhathalelo olufanelekileyo, kunye nezixhobo zokunceda uhambo lwakho.

Ukuqonda Umhlaza weMiphunga yeSeli engeNcinci

Yintoni i-NSCLC?

Umhlaza wemiphunga weseli ongengomncinci lolona hlobo luxhaphakileyo lomhlaza wemiphunga, ubalelwa malunga ne-80-85% yalo lonke uxilongo lomhlaza wemiphunga. Ihlelwe ngokweendidi ezininzi, nganye ineempawu ezizodwa ezichaphazela izicwangciso zonyango. Ukufunyaniswa kwangethuba kubalulekile ukuze kuphuculwe iziphumo. Ukuqonda uhlobo lwakho oluncinci lwe-NSCLC linyathelo eliphambili ekumiseleni eyona khosi ilungileyo unyango olungelulo oluncinci unyango lomhlaza wemiphunga kufutshane nam.

Inqanaba kunye nokuxilongwa

Ukulinganisa okuchanekileyo-ukugqiba ubungakanani bomhlaza osasazekayo-kubalulekile ekucwangciseni unyango olungelulo oluncinci unyango lomhlaza wemiphunga kufutshane nam. Oku kuquka iimvavanyo ezahlukahlukeneyo, kuquka iimaging scans (CT, PET), ibiopsy, novavanyo lwegazi. Isigaba sichaza indlela yonyango efanelekileyo kakhulu. Umzekelo, i-NSCLC yasekuqaleni inokunyangeka ngotyando lodwa, ngelixa izigaba eziphambili zinokufuna indibaniselwano yonyango.

Iinketho zonyango lwe-NSCLC

Utyando

Ukususwa ngotyando lwethumba lolona khetho lonyango lwenqanaba lokuqala le-NSCLC. Inkqubo ethile ixhomekeke kwindawo yethumba kunye nobukhulu. Oku kunokubandakanya i-lobectomy (ukususwa kwe-lung lobe), i-pneumonectomy (ukususwa komphunga uphela), okanye ukususwa kwe-wedge (ukususwa kwecandelo elincinane lemiphunga). Emva kotyando, ukubuyisela kwimeko yesiqhelo kubalulekile ukuze uchache.

Unyango ngamachiza

I-Chemotherapy isebenzisa amayeza ukubulala iiseli zomhlaza. Ihlala isetyenziswa phambi kotyando (neoadjuvant) ukuthoba ithumba, emva kotyando (adjuvant) ukuphelisa iiseli zomhlaza eziseleyo, okanye njengonyango oluphambili lwe-NSCLC ephucukileyo. Amachiza aqhelekileyo e-chemotherapy ye-NSCLC abandakanya i-cisplatin, i-carboplatin, i-paclitaxel, kunye ne-docetaxel. Iziphumo ebezingalindelekanga ziyahluka kodwa zihlala zilawuleka ngokhathalelo oluxhasayo.

Unyango ngemitha

Unyango ngemitha isebenzisa imitha ephezulu yamandla ukonakalisa nokutshabalalisa iiseli zomhlaza. Ingasetyenziswa yodwa, ngaphambi okanye emva kotyando, okanye idityaniswe nechemotherapy. Imitha yemitha yangaphandle isetyenziswa kakhulu, ukuhambisa imitha kumatshini ongaphandle komzimba. Kwezinye iimeko, i-brachytherapy (i-radiation yangaphakathi) inokuqwalaselwa.

Unyango ekujoliswe kulo

Amachiza onyango ekujoliswe kuwo ajolise kwiimolekyuli ezithile ngaphakathi kweeseli zomhlaza, eziphazamisa ukukhula kunye nokuphila kwazo. Ezi zonyango zisebenza ngokukodwa kwizigulane ze-NSCLC ezineenguqu ezithile zofuzo, ezifana ne-EGFR, ALK, okanye i-ROS1. Ukuvavanya rhoqo ukuchonga oku kuguqulwa kubalulekile ukumisela ukufaneleka kunyango olujoliswe kuyo. Imizekelo ibandakanya i-Osimertinib (Tagrisso), iCrizotinib (Xalkori), kunye ne-Afatinib (Gilotrif).

Immunotherapy

I-Immunotherapy idibanisa amajoni omzimba ukulwa nomhlaza. Isebenza ngokonyusa amandla amajoni omzimba okuqaphela kunye nokuhlasela iiseli zomhlaza. Iziyobisi ze-Immunotherapy, ezifana ne-pembrolizumab (Keytruda) kunye ne-nivolumab (i-Opdivo), ziyasebenza kwizigulane ezithile ze-NSCLC, zihlala zidibene ne-chemotherapy okanye ezinye iindlela zonyango. Iziphumo ebezingalindelekanga zinokubandakanya ukudinwa, irhashalala yesikhumba, kunye neziganeko ezimbi ezinxulumene ne-immune.

Ukufumana Unyango Olululo Kufuphi Nawe

Ukukhetha iZiko loNyango

Ukukhetha iziko le-oncology eliqeqeshiweyo kubaluleke kakhulu. Khangela amaziko aneengcali ze-oncologists ezinamava, itekhnoloji ephezulu, kunye nerekhodi elomeleleyo kunyango lwe-NSCLC. Cinga ngemiba efana nokuba kufutshane nekhaya lakho, isidima seziko, kunye nokubakho konyango olulodwa, ulingo lwezonyango, kunye neenkonzo zenkxaso. Jonga uphononongo lwe-intanethi kwaye ufune iingcebiso kugqirha wakho wokhathalelo oluphambili okanye abaqeqeshi bezempilo abathembekileyo.

Iimvavanyo zeklinikhi

Ukuthatha inxaxheba kulingo lwezonyango kunika ufikelelo kunyango olukumgangatho ophezulu ongekafumaneki ngokubanzi. Olu lingo luyilwe ngononophelo ukuvavanya amayeza amatsha kunye nokuphucula iziphumo zonyango. I-oncologist yakho inokukunceda ukuba ubone ukuba uvavanyo lweklinikhi lufanelekile kwimeko yakho ethile. Unokujonga kwakhona oovimba bovavanyo lweklinikhi njengeClinicalTrials.gov ukufumana izifundo ezifanelekileyo.

Inkxaso kunye nezibonelelo

Ukujonga ukuxilongwa komhlaza kunokuba lucelomngeni. Funa inkxaso yeemvakalelo kunye neyokusebenza ngokusebenzisa amaqela enkxaso, imibutho yomhlaza (umzekelo, i-American Lung Association, i-Lung Cancer Foundation yaseMelika), kunye neenkonzo zokucebisa. Ezi zixhobo zibonelela ngolwazi olubalulekileyo, isikhokelo, kunye nenkxaso yeemvakalelo kwizigulana neentsapho zazo.

Inqaku elibalulekileyo

Olu lwazi lulwazi ngokubanzi kwaye aluqulunqi iingcebiso zonyango. Kubalulekile ukudibana ne-oncologist eqeqeshiweyo okanye ingcali yokhathalelo lwempilo ukuze ufumane ukuxilongwa komntu, ucwangciso lonyango, kunye nokhathalelo oluqhubekayo olunxulumene noku. unyango non-incinci umhlaza wemiphunga yeseli. Olu lwazi luthiwe thaca apha aluthathi indawo yengcebiso yezonyango. Ngalo lonke ixesha ufune iingcebiso kugqirha wakho okanye omnye umboneleli wezempilo oqeqeshiweyo ngayo nayiphi na imibuzo onokuba nayo malunga nemeko yonyango.

Ngolwazi oluthe kratya okanye ukujonga iindlela zonyango kwiziko eliphambili lophando lomhlaza, ndwendwela IZiko loPhando ngoMhlaza laseShandong Baofa.