unyango non encinane yomhlaza wemiphunga unyango

Ukuqonda kunye nokuNyanga uMhlaza weMiphunga yeSeli engeNcinci

Esi sikhokelo sibanzi siphonononga umhlaza wemiphunga ongengowomncinci (NSCLC), olona hlobo luqhelekileyo lomhlaza wemiphunga. Sihlola ukuxilongwa kwayo, ezahlukeneyo unyango non-incinci unyango umhlaza wemiphunga cell iinketho, kunye nokubaluleka kokufunyanwa kwangoko kunye nokhathalelo lomntu. Funda malunga nokuhambela phambili kwamva nje kulawulo lwe-NSCLC kunye nezibonelelo ezifumanekayo kwizigulane kunye neentsapho zazo.

Ukuqonda uMhlaza weMiphunga yeSeli engeNcinci (NSCLC)

Yintoni i-NSCLC?

Umhlaza wemiphunga weseli ongengomncinci ubalelwa malunga ne-85% yalo lonke uxilongo lomhlaza wemiphunga. Ibonakala ngokukhula okungaqhelekanga kweeseli emiphungeni, ezinokusasazeka kwamanye amalungu omzimba (metastasis). Kukho iintlobo ezininzi ezisezantsi, nganye kuzo ineempawu ezizodwa ezichaphazelayo unyango non-incinci unyango umhlaza wemiphunga cell izicwangciso. Ukufunyanwa kwangoko kuphucula kakhulu iziphumo zonyango.

Imiba yoMngcipheko kwi-NSCLC

Izinto ezininzi zonyusa umngcipheko wokuphuhlisa i-NSCLC, kubandakanywa ukutshaya (unobangela ophambili), ukuvezwa kwe-asbestos kunye nezinye i-carcinogens, imbali yentsapho yomhlaza wemiphunga, kunye neemeko ezithile zofuzo. Ukuqonda le mingcipheko kubalulekile kumanyathelo othintelo kunye novavanyo lokubona kwangoko.

Ukuxilongwa kwe-NSCLC

Uxilongo ngokuqhelekileyo lubandakanya indibaniselwano yovavanyo lwemifanekiso (ezifana neeX-reyi zesifuba, i-CT scans, ne-PET scans), i-biopsy (ukuhlola iisampulu zezicubu), kunye novavanyo lwegazi. Inqanaba lomhlaza (ukuba usasazeke kangakanani na) libalulekile ekumiseleni okufanelekileyo unyango non-incinci unyango umhlaza wemiphunga cell isicwangciso.

Iinketho zonyango lwe-NSCLC

Utyando

Kwinqanaba lokuqala le-NSCLC, utyando lokususa ithumba elinomhlaza lunokuba lukhetho. Uhlobo lotyando luxhomekeke kubukhulu kunye nendawo yethumba. Ubuchwephesha botyando obungenabungozi buhlala busetyenziswa ukunciphisa ixesha lokuchacha.

Unyango ngamachiza

I-Chemotherapy isebenzisa amayeza ukubulala iiseli zomhlaza. Idla ngokusetyenziswa kunyango lwe-NSCLC ephucukileyo, rhoqo ngokudityaniswa nolunye unyango olufana nonyango olujoliswe kuyo okanye unyango lwamajoni omzimba. Imiphumo emibi iyahluka ngokuxhomekeke kumachiza athile asetyenzisiweyo.

Unyango ngemitha

Unyango ngemitha lusebenzisa imitha yemitha ephezulu ukutshabalalisa iiseli zomhlaza. Ingasetyenziswa phambi kotyando (neoadjuvant) ukuthoba ithumba, emva kotyando (adjuvant) ukubulala naziphi na iiseli zomhlaza eziseleyo, okanye njengeyona nto iphambili. unyango non-incinci unyango umhlaza wemiphunga cell kwizigulane ezingabaviwa botyando.

Unyango ekujoliswe kulo

Amachiza onyango ekujoliswe kuwo agxile kwiimolekyuli ezithile ezibandakanyekayo ekukhuleni kweeseli zomhlaza. Olu nyango lusebenza ngokukodwa kwizigulane ze-NSCLC ezinokuguqulwa kofuzo oluthile. Uvavanyo oluthe gqolo ukujonga olu tshintsho luyimfuneko kubuntu unyango non-incinci unyango umhlaza wemiphunga cell.

Immunotherapy

I-Immunotherapy idibanisa amajoni omzimba ukulwa neeseli zomhlaza. Yindlela ethembisayo ye-NSCLC ephucukileyo, ehlala isetyenziswa ngokudityaniswa nolunye unyango. Imiphumo emibi ingabandakanya iziganeko ezimbi ezinxulumene nomzimba.

UNyango oluPhezulu kunye novavanyo lwezonyango

Indawo ye-NSCLC unyango non-incinci unyango umhlaza wemiphunga cell ihlala iguquka. Unyango oluphezulu, olufana nonyango lwe-CAR T-cell kunye nezinye iindlela zenoveli, ziphandwa kulingo lwezonyango. Ukuthatha inxaxheba kulingo lwezonyango kunika ufikelelo kunyango olukwinqanaba eliphezulu kwaye kunegalelo kwinkqubela phambili yophando lomhlaza. Ngolwazi ngolingo lwezonyango, ungajongana nezixhobo ezifana neZiko loMhlaza leSizwe (https://www.cancer.gov/).

Iyeza elenzelwe wena kuNyango lwe-NSCLC

Abathungi amayeza omntu unyango non-incinci unyango umhlaza wemiphunga cell amaqhinga asekelwe kwimfuza yomntu, iimpawu zethumba, kunye nempilo iyonke. Uvavanyo lwemfuzo ludlala indima ebalulekileyo ekukhokeleni izigqibo zonyango kunye nokwandisa ukusebenza konyango. Iziko loPhando ngoMhlaza laseShandong Baofa (https://www.baofahospital.com/) inikezelwe ekuboneleleni ngokhathalelo oluphezulu lomhlaza, kusetyenziswa amayeza omntu wamva nje.

Ukhathalelo lweNkxaso kunye neZibonelelo

Ukuphila ne-NSCLC kunokuba ngumngeni, ngokomzimba nangokweemvakalelo. Ukunyamekelwa kwenkxaso kugxile ekuphuculeni umgangatho wobomi ngokulawula iintlungu, ukuxhaswa kwesondlo, ukucebisa ngokweemvakalelo, kunye nezinye izixhobo. Amaqela enkxaso yezigulane kunye noluntu lwe-intanethi lunokubonelela ngenkxaso ebalulekileyo yeemvakalelo kunye nokusebenzayo.

Isishwankathelo

Ulawulo olusebenzayo lwe-NSCLC lufuna indlela ebandakanya izinto ezininzi ezibandakanya i-oncologists, oogqirha botyando, ii-radiotherapist, kunye nezinye iingcali zempilo. Ukufunyaniswa kwangoko, kokwakho unyango non-incinci unyango umhlaza wemiphunga cell, kunye nokhathalelo olubanzi lwenkxaso lubalulekile ekuphuculeni iziphumo kunye nomgangatho wobomi kubantu abafunyanwe benesi sifo. Khumbula ukudibana nomboneleli wakho wezempilo ngeengcebiso ezenzelwe wena kunye nezicwangciso zonyango.