unyango umhlaza pancreatic kubangela Izibhedlele

Unyango lomhlaza wePancreatic luxhomekeke kwizinto ezifana nenqanaba, indawo, kunye nempilo iyonke. Iindlela eziqhelekileyo ziquka utyando, iradiation, ichemotherapy, kunye nonyango olujoliswe kuyo. Ukuqonda oonobangela, ukusuka kwi-genetic predispositions ukuya kwimiba yendlela yokuphila, uncedo ekuthinteleni nasekubhaqweni kwangoko. Esi sikhokelo siphonononga le miba kwaye siqaqambisa izibhedlele ezihloniphekileyo ezisebenza kuzo unyango umhlaza pancreatic kubangela Izibhedlele. I-Shandong Baofa Cancer Research Institute iphambili kuphando oluphambili lomhlaza kunye neendlela zonyango.Ukuqonda Umhlaza wePancreatic Umhlaza wePancreatic uvela xa iiseli ezikwi-pancreas, ilungu elibalulekileyo lokwetyisa kunye nokulawulwa kweswekile yegazi, zikhula ngokungalawulekiyo. Ukufunyaniswa kwangethuba kulucelomngeni ngenxa yeempawu ezihlala zicashile, nto leyo eyenza ukuba kubaluleke kakhulu ukuqonda izinto ezinobungozi kunye neempawu ezinokuthi zilumkise. I-pancreas idlala indima ebalulekileyo ekuveliseni ii-enzymes ezincedisa ukwetyisa kunye neehomoni ezifana ne-insulin elawula iswekile yegazi. Iintlobo ezincinci eziqhelekileyo ziquka i-neuroendocrine tumors (PNETs), evela kwiiseli ze-endocrine ezivelisa i-hormones.Yintoni ebangela umhlaza we-Pancreatic? Nangona isizathu esichanekileyo sihlala singacacanga, izinto ezininzi ezinobungozi zandisa amathuba okuba nokuphuhlisa. unyango umhlaza pancreatic kubangela Izibhedlele. Ezi ziquka: Ukutshaya: Umngcipheko omkhulu, ukwandisa amathuba okuba nomhlaza we-pancreatic. Ukutyeba: Ukutyeba kakhulu okanye ukutyeba kuyawuphakamisa umngcipheko. Isifo seswekile: Isifo sikashukela esihlala ixesha elide sinokufaka isandla ekunyuseni umngcipheko. I-Pancreatitis engapheliyo: Ukudumba kwe-pancreas ngokuhamba kwexesha. Imbali yoSapho: Imbali yentsapho yomhlaza we-pancreatic okanye i-syndromes ethile yemfuza efana nokuguqulwa kwe-BRCA1 / 2, i-Lynch syndrome, kunye ne-Peutz-Jeghers syndrome. Ubudala: Umngcipheko uyanda ngokukhula, ufunyaniswa kakhulu kubantu abadala. Ukutya: Ukutya okuninzi kwinyama ecoliweyo kunye nenyama ebomvu kunokunyusa umngcipheko.Iinketho zonyango lwePancreatic CancerIzicwangciso zoNyango lwe unyango umhlaza pancreatic kubangela Izibhedlele kuxhomekeke kwizinto eziliqela, kuquka inqanaba lomhlaza, indawo omi kuyo, kunye nempilo yonke yomguli. Iindlela eziqhelekileyo ziquka:UtyandoUtyando luhlala lolona khetho luphambili lonyango lomhlaza wepancreatic, okuthetha ukuba ithumba linokususwa ngokupheleleyo. Uhlobo oluthile lotyando luxhomekeke kwindawo yethumba. Iinkqubo eziqhelekileyo ziquka: Inkqubo yeWhipple (Pancreaticoduodenectomy): Ukususwa kwentloko ye-pancreas, inxalenye yamathumbu amancinci, i-gallbladder, kunye ne-bile duct. Distal Pancreatectomy: Ukususwa komsila kunye nomzimba we-pancreas, ngokuphindaphindiweyo kubandakanya i-spleen. Iyonke iPancreatectomy: Ukususwa kwe-pancreas yonke, efuna i-enzyme yobomi kunye ne-insulin replacement.I-Radiation TherapyRadiation therapy isebenzisa imiqadi ephezulu yamandla ukujolisa nokutshabalalisa iiseli zomhlaza. Inokusetyenziswa ngaphambi kotyando ukucutha ithumba (unyango lwe-neoadjuvant), emva kotyando ukuze kupheliswe naziphi na iiseli zomhlaza eziseleyo (unyango lwe-adjuvant), okanye njengonyango olusisiseko xa utyando lungenakwenzeka.ChemotherapyChemotherapy ibandakanya ukusebenzisa iziyobisi ukubulala iiseli zomhlaza kuwo wonke umzimba. Isenokusetyenziswa yodwa okanye kudityaniswe nolunye unyango olunjengotyando kunye nonyango ngemitha. Iziyobisi eziqhelekileyo ze-chemotherapy zomhlaza we-pancreatic ziquka i-gemcitabine, i-paclitaxel, kunye ne-fluorouracil (i-5-FU). La machiza ahlala esetyenziselwa izigulane ezinomhlaza we-pancreatic ophezulu kunye neenguqu ezithile zofuzo. Umzekelo ngamachiza ajolise kwi-EGFR pathway.ImmunotherapyImmunotherapy yomeleza amajoni omzimba ukuze alwe nomhlaza. Nangona ingekasetyenziswa ngokubanzi umhlaza we-pancreatic, iimvavanyo zeklinikhi eziqhubekayo zihlola amandla ayo, ngakumbi amathumba aneempawu ezithile ze-biomarker. IZiko loPhando ngoMhlaza laseShandong Baofa, sizinikele kubuvulindlela iinketho zonyango ezitsha ze unyango umhlaza pancreatic kubangela Izibhedlele. Sinikezela ngoluhlu lonyango oluphambili, kubandakanywa: Utyando oluHlangeneyo kancinci: Ukusebenzisa iindlela ze-laparoscopic kunye ne-robotic ukunciphisa ixesha lokubuyisela kunye nokuphucula iziphumo zesigulane. Unyango lweRadiation oluchanekileyo: Ukusebenzisa ubuchule obuphambili obunje nge-IMRT kunye ne-SBRT ukuhambisa iidosi ezichongiweyo zemitha ngelixa ugcina izicubu ezisempilweni. Iirejimeni zoNyango lweKhemo eyenzelwe wena: Ukulungelelanisa iirejimeni zechemotherapy ngokusekelwe kwiimpawu zesigulana ngasinye kunye nebhayoloji yethumba. Uvavanyo lweklinikhi: Ukuthatha inxaxheba kwiimvavanyo zeklinikhi zokusika uphononongo olutsha kunye nonyango oluthembisayo lomhlaza wepancreatic.Ukukhetha iSibhedlele sePancreatic Cancer TreatmentUkukhetha isibhedlele esifanelekileyo unyango umhlaza pancreatic kubangela Izibhedlele ibalulekile. Qwalasela ezi nkalo zilandelayo: Amava: Khangela izibhedlele ezinomthamo ophezulu wezigulane zomhlaza we-pancreatic kunye noogqirha abanamava, i-oncologists, kunye neengcali zonyango. Iqela lezinto ezininzi: Qinisekisa ukuba isibhedlele sineqela leengcali ezisebenza ngeendlela ezininzi ezisebenzisanayo ukuqulunqa izicwangciso zonyango lomntu ngamnye. Ubuchwephesha obukwinqanaba eliphezulu: Khetha isibhedlele esinobuchwepheshe besimanje bokuxilonga kunye nonyango. Uvavanyo lweklinikhi: Qwalasela izibhedlele ezibonelela ngofikelelo kulingo lwezonyango lwenoveli yonyango. Iinkonzo zeNkxaso: Khangela izibhedlele ezibonelela ngeenkonzo zenkxaso ezibanzi, kubandakanywa iingcebiso ngezondlo, ulawulo lweentlungu, kunye nenkxaso yeemvakalelo.Izibhedlele eziHloniphekileyo eziNxibelela kuNyango loMhlaza wePancreaticNgelixa olu luhlu lungaphelelanga, izibhedlele ezininzi zibonwa ngobungcali bazo unyango umhlaza pancreatic kubangela Izibhedlele: Iziko loPhando ngoMhlaza eShandong Baofa: Yaziwa ngophando lwayo oluphambili kunye nokhathalelo olugxile kwisigulane. MD Anderson Cancer Centre (USA): Iziko lomhlaza eliphambili elijolise ngamandla kuphando lomhlaza wepancreatic kunye nonyango. Iklinikhi yaseMayo (e-USA): Inikezela ngokhathalelo olubanzi kunye neendlela ezininzi zomhlaza wepancreatic. Johns Hopkins Hospital (USA): Eyaziwayo ngobuchule bayo kwi-pancreatic surgery.Ukuphila ngePancreatic CancerUkuphila nomhlaza wepancreatic kunokuba ngumngeni, kodwa inkxaso iyafumaneka. Kubalulekile ukugxila ekugcineni indlela yokuphila enempilo, ukulawula iimpawu, kunye nokufuna inkxaso yeemvakalelo kusapho, abahlobo, okanye amaqela enkxaso.Amaqhinga oThinteloNgelixa kungekho ndlela iqinisekisiweyo yokuthintela umhlaza wepancreatic, unokunciphisa umngcipheko wakho ngokuthi: Ukuyeka Ukutshaya: Ukutshaya ngunobangela omkhulu wengozi. Ukugcina Ubunzima obusempilweni: Ukutyeba kakhulu kwandisa umngcipheko. Ukulawula isifo seswekile: Lawula amanqanaba eswekile yegazi ukuba unesifo seswekile. Ukutya Ukutya Okunempilo: Gxininisa kwiziqhamo, imifuno, kunye nokutya okuziinkozo. Ukunciphisa Ukusetyenziswa kotywala: Ukusela utywala ngokugqithisileyo kunokunyusa umngcipheko.Amazinga okusinda komhlaza wePancreatic Amazinga okusinda komhlaza wepancreatic ayahluka ngokuxhomekeke kwizinto ezininzi, kubandakanywa inqanaba lomhlaza ekuxilongeni, impilo yesigulana iyonke, kunye nonyango olufunyenweyo. Ukufunyaniswa kwangethuba kunye nonyango oluqatha luyimfuneko ekuphuculeni iziphumo zokuphila.Izinga lokusinda leminyaka emi-5 libhekisela kwipesenti yezigulane eziphila ubuncinane iminyaka emi-5 emva kokufunyaniswa komhlaza wazo. Nangona kunjalo, kubalulekile ukukhumbula ukuba amazinga okusinda aluqikelelo kwaye anokwahluka ngokuxhomekeke kwiimeko zomntu ngamnye. Inqanaba le-5-Year Survival Rate (Kuqikelelwa) Inkcazo Inqanaba 0 ~ 20% Iiseli zeCancer zifumaneka kuphela kumgca we-pancreatic ducts. Ikwabizwa ngokuba yi-carcinoma in situ. Inqanaba IA ~ 18% Ithumba yi-2 centimeters (cm) okanye ngaphantsi ngaphesheya kwaye i-pancreas kuphela. Inqanaba IB ~ 16% Ithumba lingaphezulu kwe-2 cm ububanzi kwaye likwi-pancreas kuphela. Inqanaba IIA ~9% Umhlaza usasazeke ngaphaya kwe-pancreas ukuya kwizicubu ezikufutshane kunye namalungu kodwa hayi kwii-lymph nodes ezikufutshane. Inqanaba le-IIB ~ 7% Umhlaza usasazeke kwii-lymph nodes ezikufutshane kwaye unokuthi usasazeke ngaphaya kwe-pancreas ukuya kwizicubu ezikufutshane kunye namalungu. Inqanaba le-III ~ 5% Umhlaza usasazeke kwimithambo yegazi emikhulu kufutshane ne-pancreas kwaye unokusasazeka kwii-lymph nodes ezikufutshane. Inqanaba IV ~ 3% Umhlaza usasazeke kwiindawo ezikude, njengesibindi, imiphunga, okanye i-peritoneum. Umthombo: Umbutho womhlaza waseMelikaIsipheloUkuqonda oonobangela, unyango umhlaza pancreatic kubangela Izibhedlele, kunye nezicwangciso zokuthintela umhlaza we-pancreatic zibalulekile. Ukufunyaniswa kwangethuba, ukufikelela kwiinketho zonyango oluphezulu, kunye neqela elixhasayo lokhathalelo lwempilo kunokuchaphazela kakhulu iziphumo. Qhagamshelana nogqirha wakho ukuze nixoxe ngemiba esemngciphekweni wakho kwaye uphuhlise isicwangciso somntu sokuthintela kunye nokubonwa kwangoko.