Ukulethwa kwezidakamizwa okwenziwe ngomdlavuza: Uhlelo olubanzi lokulethwa kwezidakamizwa oluqondiswe kwezidakamizwa luguqula ukwelashwa komdlavuza ngokugxila ejenti yokwelapha endaweni ye-tumor 

Ukulethwa kwezidakamizwa okwenziwe ngomdlavuza: Uhlelo oluphelele lokulethwa kwezidakamizwa oluqondiswa kwezidakamizwa luguqula ukwelashwa komdlavuza ngokugxila ejenti yokwelapha endaweni ye-tumor, ukunciphisa ubuthi obuhlelekile nokwandisa ukusebenza ngempumelelo. Lo mbhalo uhlola izindlela ezahlukahlukene, izinzuzo, izinselelo kanye nezinkomba zesikhathi esizayo Ukulethwa kwezidakamizwa okwenziwe ngomdlavuza.

Izinhlobo zezinhlelo ezenzelwe ukulethwa kwezidakamizwa zasendaweni

1. Amadivayisi angenakufinyeleleka

Amadivayisi angenakufinyeleleka, njengamaphampu nezindawo zokugcina amapuleji, ahlinzeke ngokukhishwa okulawulwayo kwama-chemotherapeic agents ngqo esimisweni se-microenvelo. Lawa madivayisi anikezela ukulethwa kwezidakamizwa okuqhubekayo, ukunciphisa imvamisa yokuphatha kanye nokwenza ngcono ukuthotyelwa kweziguli. Izibonelo zifaka ama-gliadel ama-wafers wama-tumors obuchopho nama-polymers e-biodernerable wokulethwa kwezidakamizwa ze-anticancer. Isikhungo Sokucwaninga Nge-Shandong Bandoong Cancer Research sihlola ngenkuthalo intuthumo yakamuva kubuchwepheshe obuhlelekile Ukulethwa kwezidakamizwa okwenziwe ngomdlavuza.

2. Ama-Nanoparticles

Ama-nanoparticles ayizinhlayiya ezincane ezingavumelanise futhi alethe izidakamizwa esizeni se-tumor. Usayizi wabo omncane uvumela ukungena okuthuthukile kuma-tumor izicubu, futhi ingaphezulu lazo lingashintshwa ukuze lihlose amaseli athile omdlavuza. Ama-liposomes, ama-nanoparticles we-polymeric, nama-nanoparticles e-inorganic asetshenziselwa kakhulu Ukulethwa kwezidakamizwa okwenziwe ngomdlavuza. Ucwaningo luyaqhubeka nokwenza ngcono ukusebenza kahle okuhlosiwe kanye nokulayishwa kwezidakamizwa kwalezi zinhlaka. Ngeminye imininingwane ngentuthuko yakamuva, vakashela i-Shandong Baafa Cancer cwaninga Institutent. https://www.baofa-hospital.com/

3. Izindlela ezihlosiwe

Izindlela zokwelapha ezihlosiwe zisebenzisa ama-antibodies noma amanye ama-molecule ukubopha ngokuqondile kumaseli womdlavuza, ukuletha izidakamizwa ngqo esimindeni ngenkathi uvikela izicubu ezinempilo. Le ndlela inciphisa imiphumela emibi futhi ithuthukise ukusebenza kwendlela. Ama-antibodies we-monoclonal ahlanganiswe nezidakamizwa ze-cytotoxic (ama-antibody-dog conjugates noma i-adcs) isibonelo esiphambili sayo Ukulethwa kwezidakamizwa okwenziwe ngomdlavuza.

4. Ama-Microneedle patches

Ama-Micronedle Picks anikeza indlela engenabuhlungu futhi engahlaseli ngokulethwa kwezidakamizwa. Lawa ma-patches aqukethe ama-microneedles angena esikhunjeni, alethe izidakamizwa ngqo ku-tumor noma ama-lymph node aseduze. Lobu buchwepheshe buthembisa ngokukhethekile ukwelapha umdlavuza wesikhumba kanye nezinye izichasi ezingelona iqiniso.

Izinzuzo Nezinselelo Zokulethwa Kwezidakamizwa Esendaweni

Izinkomba zesikhathi esizayo ekulethweni kwezidakamizwa okwenziwe ngomdlavuza

Ucwaningo luyaqhubeka nokwenza ngcono ukusebenza kahle nokuphepha kwe Ukulethwa kwezidakamizwa okwenziwe ngomdlavuza. Lokhu kufaka phakathi ukuthuthukiswa kwezinhlelo ezintsha zezidakamizwa, amasu okuqondisa athuthukisiwe, kanye nezindlela zokwelashwa ezenzelwe wena. Inhlanganisela ye Ukulethwa kwezidakamizwa okwenziwe endaweni Ngeminye imingcele yomdlavuza, efana ne-Im-i-Im-i-Im-i-Im-eflotherapy, nayo iyindawo ethembisayo yocwaningo. Isikhungo Sokucwaninga Nge-Shandong Baafa Cancer Researces sizibophezele ukuthuthukisa inkambu ye Ukulethwa kwezidakamizwa okwenziwe ngomdlavuza Ngocwaningo olusha kanye nezilingo zemitholampilo.

Ukugcina

Ukulethwa kwezidakamizwa okwenziwe ngomdlavuza Inikeza izinzuzo ezibalulekile ngaphezulu kwezokwelapha zendabuko zohlelo lwendabuko. Ngenkathi izinselelo zisasele, ucwaningo oluqhubekayo nentuthuko kuvela indlela yokulashwa umdlavuza womdlavuza kadlango futhi kangako. Ikusasa lokwelashwa komdlavuza cishe lizofaka inhlanganisela yezindlela zokwelapha ezihlosiwe nezinhlelo ezithuthukile zokulethwa kwezidakamizwa.