Ua rau Pancreatic Cancer: Nkag siab qhov txaus ntshai 

Mob qog noj ntshav pancreatic yog ib hom kab mob nyuaj uas muaj ntau yam paub thiab xav tias ua rau. Txawm hais tias qhov laj thawj tseeb feem ntau tsis paub, qee yam kev pheej hmoo tuaj yeem ua rau muaj kev pheej hmoo ntawm kev tsim mob qog noj ntshav. Cov yam tseem ceeb no muaj xws li los ntawm cov caj ces predispositions mus rau txoj kev ua neej. To taub cov no ua rau mob qog noj ntshav pancreatic yog ib qho tseem ceeb heev rau kev tshawb nrhiav thiab kev tiv thaiv thaum ntxov. Peb lub hom phiaj muab cov ntaub ntawv raug thiab hloov tshiab los pab tib neeg txiav txim siab paub txog lawv txoj kev noj qab haus huv.

Pancreatic Cancer yog dab tsi?

Ua ntej dhia mus rau hauv lub ua rau mob qog noj ntshav pancreatic, nws yog ib qho tseem ceeb kom nkag siab txog tus kab mob nws tus kheej. Mob qog noj ntshav pancreatic tshwm sim thaum cov hlwb hauv pancreas, ib qho khoom nruab nrog nyob tom qab lub plab, pib loj hlob ntawm kev tswj. Cov qog nqaij hlav cancer no tuaj yeem tsim cov qog thiab muaj feem kis mus rau lwm qhov hauv lub cev.

Cov Yam Tseem Ceeb Tseem Ceeb & Ua rau Mob Cancer Pancreatic

Kev haus luam yeeb

Kev haus luam yeeb yog ib qho tseem ceeb tshaj plaws ntawm kev hloov pauv kev pheej hmoo rau mob qog noj ntshav pancreatic. Cov kev tshawb fawb tau pom tsis tu ncua tias cov neeg haus luam yeeb muaj ob mus rau peb npaug ntau dua yuav tsim mob qog noj ntshav pancreatic piv rau cov tsis haus luam yeeb. Qhov kev pheej hmoo nce ntxiv nrog rau cov luam yeeb haus luam yeeb thiab lub sijhawm ntawm kev haus luam yeeb. Kev txiav luam yeeb tuaj yeem txo qhov kev pheej hmoo no.

Mob ntshav qab zib

Ntshav qab zib mellitus, tshwj xeeb tshaj yog cov ntshav qab zib ntev ntev, cuam tshuam nrog kev pheej hmoo siab ntxiv mob qog noj ntshav pancreatic. Ob hom ntshav qab zib hom 1 thiab hom 2 tau txuas nrog qhov kev pheej hmoo siab ntxiv. Txawm hais tias qhov tseeb mechanism tsis to taub tag nrho, nws ntseeg tau tias cov yam ntxwv zoo li insulin tsis kam thiab mob ntev tuaj yeem ua lub luag haujlwm. Kev tswj cov ntshav qab zib thaum ntxov tuaj yeem pab txo qis kev pheej hmoo.

Kev rog rog

Kev rog rog, tshwj xeeb tshaj yog thaum ua ke nrog lwm yam kev pheej hmoo xws li kev haus luam yeeb thiab ntshav qab zib, tuaj yeem ua rau muaj kev pheej hmoo mob qog noj ntshav pancreatic. Lub cev hnyav dhau lawm tuaj yeem ua rau mob ntev thiab ua rau cov tshuaj hormonal tsis txaus, uas tuaj yeem ua rau muaj tus kabmob. Kev tuav lub cev hnyav los ntawm kev noj zaub mov thiab kev tawm dag zog yog qhov tseem ceeb rau kev noj qab haus huv tag nrho thiab kev tiv thaiv kab mob qog noj ntshav.Lub koom haum Shandong Baofa Cancer Research Institute hais txog qhov tseem ceeb ntawm kev noj zaub mov kom zoo hauv kev tiv thaiv kab mob cancer. Xav paub ntau ntxiv txog peb qhov kev tshawb fawb.

Mob pancreatitis ntev

Cov kab mob pancreatitis ntev, qhov mob ntev ntev ntawm tus txiav, yog qhov paub txog kev pheej hmoo rau mob qog noj ntshav pancreatic. Kev rov ua mob tuaj yeem ua rau cov kab mob pancreatic puas thiab ua rau muaj kev hloov pauv qog noj ntshav. Cov tsos mob ntawm tus mob pancreatitis muaj xws li haus cawv hnyav, mob plab, thiab qee yam kab mob hauv caj ces.

Genetic Predisposition & Family History

Cov yam ntxwv ntawm caj ces ua lub luag haujlwm tseem ceeb hauv qee kis mob qog noj ntshav pancreatic. Cov tib neeg uas muaj keeb kwm ntawm tsev neeg muaj tus kab mob, tshwj xeeb yog cov neeg uas muaj ntau tus txheeb ze cuam tshuam, muaj kev pheej hmoo siab dua. Qee yam kev mob caj ces, xws li BRCA1, BRCA2, PALB2, ATM, thiab Lynch syndrome, yog txuam nrog kev pheej hmoo siab ntawm mob qog noj ntshav pancreatic.

Hnub nyoog

Kev pheej hmoo ntawm mob qog noj ntshav pancreatic nce nrog hnub nyoog. Feem ntau raug kuaj pom hauv cov neeg muaj hnub nyoog tshaj 65 xyoos. Txawm hais tias lub hnub nyoog nws tus kheej tsis yog qhov ua rau ncaj qha, qhov sib txuam ua rau muaj feem cuam tshuam rau lub neej yuav ua rau muaj tus kab mob.

Haiv neeg

Hauv Tebchaws Meskas, African Asmeskas muaj qhov xwm txheej ntau dua mob qog noj ntshav pancreatic piv rau Caucasians. Cov laj thawj ntawm qhov tsis sib xws no tsis to taub tag nrho tab sis yuav muaj kev sib txuas ntawm caj ces, ib puag ncig, thiab kev lag luam hauv zej zog.

Noj zaub mov

Thaum lub luag hauj lwm ntawm kev noj haus nyob rau hauv mob qog noj ntshav pancreatic tseem tab tom tshawb nrhiav, qee qhov kev tshawb fawb qhia tias kev noj zaub mov muaj xim liab thiab cov nqaij ua tiav thiab cov txiv hmab txiv ntoo thiab zaub tsawg tuaj yeem ua rau muaj kev pheej hmoo. Kev noj zaub mov nplua nuj nyob hauv cov nplej, txiv hmab txiv ntoo, thiab zaub feem ntau pom zoo rau kev noj qab haus huv tag nrho thiab kev tiv thaiv kabmob kheesxaws.

Tshuaj Tiv Thaiv

Kev cuam tshuam rau qee yam tshuaj, xws li tshuaj tua kab, tshuaj zawv plaub hau, thiab lwm yam tshuaj lom neeg, tau txuas nrog kev pheej hmoo siab ntawm mob qog noj ntshav pancreatic hauv qee qhov kev tshawb fawb. Kev ua haujlwm raug rau cov tshuaj no yuav tsum tau txo qis thaum ua tau.

Lwm Yam Muaj Peev Xwm Muaj Peev Xwm

Kev haus cawv

Kev haus dej cawv ntau yog qhov ua rau mob pancreatitis ntev, uas, raws li tau hais dhau los, yog qhov pheej hmoo rau mob qog noj ntshav pancreatic. Kev txwv tsis pub haus cawv tuaj yeem txo qhov kev pheej hmoo ntawm tus mob pancreatitis thiab tom qab ntawd txo qhov kev pheej hmoo ntawm mob qog noj ntshav pancreatic.

Gallstones

Thaum tsis yog ib qho ncaj qha ua rau mob qog noj ntshav pancreatic, gallstones tuaj yeem ua rau mob pancreatitis, uas yog qhov paub txog kev pheej hmoo. Kev tswj cov kab mob gallstone tuaj yeem pab tiv thaiv kab mob pancreatitis thiab ua rau txo qis kev pheej hmoo ntawm mob qog noj ntshav pancreatic.

Nkag siab txog koj txoj kev pheej hmoo thiab kev tiv thaiv

Paub txog ua rau mob qog noj ntshav pancreatic thiab koj tus kheej cov xwm txheej txaus ntshai yog qhov tseem ceeb rau kev tiv thaiv thiab tshawb pom ntxov. Txawm hais tias qee qhov kev pheej hmoo, xws li caj ces, tsis hloov pauv, lwm tus, xws li haus luam yeeb, rog, thiab noj zaub mov, tuaj yeem tswj tau. Kev kuaj xyuas tsis tu ncua thiab kev tshuaj ntsuam xyuas yuav raug pom zoo rau cov tib neeg uas muaj kev pheej hmoo siab, xws li cov neeg muaj keeb kwm ntawm tsev neeg muaj tus kab mob. Ntawm no yog ib lub rooj summarizing modifiable risk factor:

Xaus

Thaum lub caij nyoog ua rau mob qog noj ntshav pancreatic tsis to taub tag nrho, txheeb xyuas thiab tswj cov kev pheej hmoo tuaj yeem ua lub luag haujlwm tseem ceeb hauv kev tiv thaiv thiab tshawb pom ntxov. Los ntawm kev coj noj coj ua hauv kev noj qab haus huv, zam kev paub txog cov kab mob carcinogens, thiab kev kuaj xyuas tsis tu ncua, cov tib neeg tuaj yeem txo lawv txoj kev pheej hmoo ntawm tus kab mob no. Yog xav paub ntxiv lossis cov lus nug, thov mus saib Shandong Baofa Cancer Research Institute.

Cov ntaub ntawv

1. American Cancer Society. (n.d.). Pancreatic Cancer Risk Factors. https://www.cancer.org/cancer/types/pancreatic-cancer/causes-risks-prevention/risk-factors.html
2. National Cancer Institute. (n.d.). Pancreatic Cancer Prevention (PDQ?)–Patient Version. https://www.cancer.gov/types/pancreatic/patient/pancreatic-prevention-pdq