Ultra-shoma incision yakasarudzika intratumoral chemoimmunotherapy: Nhungamiro yakazara 

Ultra-shoma incision yakasarudzika intratumoral chemoimmunotherapy Icho chirwere che cancer cancer yekubatira ichisanganisira kusanganisa zvakanyanya kuvhiyiwa nekemoimmunotherapy zvakananga mubundo. Iyi nzira inovavarira kuwedzera kurapwa kwekurapa apo kuderedza mhedzisiro, zvinogona kutungamira kudzvanyiswa kwemarasha. Ichi chinyorwa chinopera muzvinyorwa zvehunyanzvi iyi, kusanganisira nheyo dzaro, maitiro, zvakanaka, uye mirayiridzo yemberi.

Kunzwisisa intratumoral chemoimmunotherapy

Intratumoral chemoimmunotherapy inosanganisira zvakananga kujekesa chemoirevera mumiriri uye / kana kuti immunomtherapetic vamiririri kupinda mumujasi. Iyi yekufambisa inobviswa inobvumira kukwira kwepamusoro kwemishonga kuti isvike iyo bundu resaiti, kuderedza kuratidzwa kwehurongwa uye kupfupika kunoenzaniswa neyechinyakare intravenous chemotherapy. Zvinowanzoshandiswa mukubatana pamwe nezvimwe kurapwa sekuvhiyiwa kana kurapa radiation.

Kushanduka kwe cancer kurapwa

Cancer Cancer Kurapa, senge systemic chromotherapy uye radiation kurapwa, kazhinji zvinokanganisa muviri wese, zvichitungamira kune zvakakosha mhedzisiro. Intratumoral Therapy inomiririra chinjana kusvika kune zvimwe zvakanangana uye zvakasarudzika nzira. Nekurapa kwekutarisa zvakananga pane bundu, zvinangwa kusevha zvinhu zvine hutano uye kuvandudza hupenyu hwemurwere. Shandong baofa cancer researching Institute yakazvipira kuhuserwa mundima iyi.

Iyo 'Ultra-shoma incision' nzira

Iyo 'Ultra-shoma incision' chimiro chinoreva nzira yekuvhiya inoshandiswa kuwana iyo bundu renyaya ye jekiseni. Izvi zvinowanzo kusanganisira zvidiki zvidiki, zvinowanzotungamirirwa newangu matekinoroji senge ultrasound kana ct scans, kuve nechokwadi chekutumira chaiko kwevamiriri vekurapa. Iyo miviri inosangana nechimiro chehunhu hunopa mukana wekukurumidza kudzorera nguva uye zvakaderedzwa post-kushanda kwekushanda.

Zvakanakira Kuvhiyiwa Kwese Kusvirwa

• Mazhizha madiki
• Kurwadziwa kushoma
• Pfupi chipatara gara
• Kukurumidza kupora
• Kuderedzwa njodzi yekumanikidzwa

Yakasarudzika Chemoimmunotherapy: Kugadzirisa kurapwa kune munhu

Kusarudzika chinhu chakakosha cheiyi nzira. Asati arapwa, bundu remurwere rinoongororwa kuti azivise hunhu hwayo, hwakadai sekutengesa kwevanhurume nemarara. Ruzivo urwu runobva rwunosarudza kusarudzira zvakanyanya zvinobudirira chechipothepicic uye immunomtherapeutic vamiririri veiyo bundu. Iyi nzira yakasarudzika inokwidza mikana yekubudirira kurapwa uye kuderedza njodzi yekuita zvakaipa.

Basa reBiomemarker Ongororo

Biomemaken kuongororwa kwakakosha kune yakasarudzika chekoimmunotherapy. Nekuzivisa zvakanyatsonaka baemarkers mujoka, varapi vanogona kufanotaura kuti izvo zvinodhaka zvinonyanya kushanda. Semuenzaniso, PD-L1 chirevo chinogona kuratidza mukana wekutevera kune imwe immunomotharies.

Maitiro: nhanho-ne-nhanho

The the Ultra-shoma incision yakasarudzika intratumoral chemoimmunotherapy Maitiro anowanzo kusanganisira matanho anotevera:

1. Pre-Option Ongororo: Murwere anowana kunyatsoongorora, kusanganisira kufungidzira fundo uye biomemarker kuongorora.
2. Kuronga Kuronga: Zvichienderana nekuongororwa, chirongwa chakarongwa chakarongeka chinogadzirwa, kutaura nezve chemoitothecic uye immunomthERIPETIC vamiririri kuti vashandiswe.
3. Maitiro: Murwere anoitwa nenzira inonyanya kusanganisa maitiro, panguva iyo mishonga inoiswa mumubhadharo zvakananga muhudyu pasi pekutungamirirwa nemifananidzo.
4. Kutumira-kushanda kwekutarisa: Murwere anotariswa zvakanyanya kune chero mhedzisiro kana matambudziko. Tevera-up fungidziro fundo dzinoitwa kuti uongorore mhinduro yekurapwa.

Zvinogona kubatsira Ultra-shoma incision yakasarudzika intratumoral chemoimmunotherapy

Iyi nzira inokanganisa inopa mabhenefiti anoverengeka anogona kuenzaniswa nekenza yekarisheni yekenza:

• Yakavandudzwa Kubata: Kushamwaridzana kwakakwirira kwezvinodhaka pakateya nzvimbo.
• Yakaderedzwa Kutakura: Yakaderera systemic kuratidzwa ku chemotherapy.
• Kurapa Kwakasarudzika: Yakagadzirirwa kune iyo yemurwere emurwere maitiro.
• Zvishoma zvinosangana: Kukurumidza kupora uye kushoma kurwadziwa.
• Zvinogona kuita kukurudzira kwemuviri: Instatunihral Kuunza yeVamiriri Vamiririri vanogona kukurudzira immune system kurwisa bundu.

Mienzaniso yeCancers Yakabatwa neIntratumoral Chemoimmunotherapy

Nepo tsvakiridzo iri kuenderera, Ultra-shoma incision yakasarudzika intratumoral chemoimmunotherapy yakaratidza vimbiso yekurapa dzakasiyana-siyana dzekurapa, kusanganisira:

• Melanoma
• Hepatocely carcinoma (chiropa cancer)
• Kenza yemazamu
• Kenza yemapapu
• Dzimwe tumati dzakasimba

Clinical Tiedzo data uye tsvakiridzo

Miedzo yekiriniki yakawanda iri kuongorora yekuongorora kuchengetedza uye kushanda kwe Ultra-shoma incision yakasarudzika intratumoral chemoimmunotherapy. Mhedzisiro yekutanga ndeyekuvimbisa, nezvimwe zvidzidzo zvinoratidza kukosha kwehunyanzvi hwekutora uye nekuvandudzwa kwekupona kwevarwere kunobatwa neiyi nzira. Semuenzaniso, fundo yakabudiswa mu Chinyorwa cheClinical Oncology yakaratidza kuvandudzwa kwakakosha mukupona kwevarwere nevarwere neyakaenda melanoma kwakarapwa neIntratumoral immunotherapy vachienzaniswa neaya vanobatwa nehurongwa hwezvirongwa ^[1].

Ramangwana reIntratumoral Chemoimmunotherapy

Munda weIntratumoral Chemoimmunotherapy anokurumidza kubuda. Mafambiro emangwana anosanganisira:

• Kuvandudzwa kwetsva uye zvakanyanya zvinobudirira chechipothepeutic uye immunomothapeutic vamiririri.
• Nzira dzakavandudzwa dzekurapa kurapwa kwakavakirwa pane tumor hunhu.
• Kusanganiswa kwekunyaradza kurapwa pamwe nedzimwe cancer kurapwa, kwakadai sekurapa radiation uye zvakarongedzwa kurapwa.
• Kushandisa nanotechnology kununura zvinodhaka zvakanyanya kune iyo bundu saiti.

Kusarudzwa kwemurwere uye kufunga

Havasi vese varwere vakasarudzika vakakodzera Ultra-shoma incision yakasarudzika intratumoral chemoimmunotherapy. Zvinhu zvekufunga zvinosanganisira:

• Tumor saizi nenzvimbo
• Hutano hweMurwere hwese
• PROPER CERCER Kurapa
• Kuvapo kweiyo chaiyo biemarkers

Kuongorora kwakakwana neboka revanhu vazhinji veAltidistary revanovhiringidza, vanovhiya, uye mamwe ma nyanzvi anokosha kuti uone kuti nzira iyi yekurapa yakakodzera kune imwe nzira yakakodzera kune mumwe murwere. Varwere vachitsvaga ruzivo rwakawanda vanogamuchirwa kuti vataure nesu kuti tibvunze kubvunza kwekutanga.

Njodzi dzinogona kuitika uye mhedzisiro

Sezvineiwo ne chero maitiro ekurapa, Ultra-shoma incision yakasarudzika intratumoral chemoimmunotherapy inotakura dzimwe njodzi uye zvinogona kuitika mhedzisiro. Izvi zvinogona kusanganisira:

• Kurwadziwa uye kuzvimba pajecha rejekiti
• Utachiona
• Kubuda ropa
• Allergic maitiro kune zvinodhaka
• Systemic mhedzisiro yemakemotherapy

Izvo zvakakosha kuti tikurukure nengozi idzi nachiremba wako usati warapwa.

Mutengo uye kuwanikwa

Mutengo we Ultra-shoma incision yakasarudzika intratumoral chemoimmunotherapy inogona kusiyana zvichienderana nemishonga yakatarwa inoshandiswa, kuomarara kwehunhu, uye nzvimbo yenzvimbo yekurapa. Izvo zvakakosha kuti tikurukure mutengo neako hutano hwehutano mupi uye neinishuwarenzi kambani. Kuwanikwa kunogona kuve chinhu, sezvo kurapwa uku kusiri kuwanikwa zvachose pamatunhu echechi dzese.

Mhedziso

Ultra-shoma incision yakasarudzika intratumoral chemoimmunotherapy inomiririra nzira itsva yekuvimbisa kune kurapwa kenza. Nekubatanidza zvishoma kusanzwisisika kuvhiya neyechemoimunotherapy, inopa mukana wekuvandudza kugona, kuderedza chifukidzo, uye kusimudzira hupenyu hwemurwere. Nepo kumwezve kutsvagisa kunodiwa, iyi nzira yekutsva inobata yakanyanya kuvimbisa ramangwana rekanza yekutarisirwa nekenza. Panguva Shandong baofa cancer researching Institute, isu tinoramba takazvitsaurira kupayona mu cancer kurapwa uye kupa varwere neakanakisa kukosha. Bata nesu kuti tidzidze zvakawanda nezve yedu yakazara cancer kurapwa sarudzo.

Mareferensi

1 Ribas, A., et al. (2018). Intratumoral immunotsotherapy. Chinyorwa cheClinical Oncology, 36 (9), 919-927.