Iimpawu zePancreatic Cancer: Isikhokelo esiBanzi 

Umhlaza wePancreatic ihlala ibonakalisa iimpawu ezingacacanga ezinokuthi ziphazame ngokulula nezinye iimeko. Ukufunyaniswa kwangethuba kubalulekile ekuphuculeni iziphumo zonyango. Iimpawu eziqhelekileyo ziquka intlungu yesisu, i-jaundice, ukulahleka kwesisindo, kunye nokutshintsha kwimikhwa yamathumbu. Ukuba ufumana nayiphi na yezi mpawu, kubalulekile ukubonisana nochwepheshe bezempilo ukuze bavavanye kwaye baxilongwe.

Ukuqonda uMhlaza wePancreatic

Umhlaza wePancreatic iqala kwi-pancreas, ilungu elisemva kwesisu elivelisa i-enzymes yokugaya kunye nehomoni yokulawula iswekile yegazi. Kukho iintlobo ezahlukeneyo zomhlaza wepancreatic, kwaye i-adenocarcinoma yeyona ixhaphakileyo.

Imiba yoMngcipheko kuMhlaza wePancreatic

Ziliqela izinto ezinokonyusa umngcipheko wokukhula umhlaza wepancreatic, kuquka:

• Ukutshaya
• Ukutyeba ngokugqithisileyo
• Isifo seswekile
• I-pancreatitis engapheliyo
• Imbali yosapho lwe umhlaza wepancreatic
• Iimpawu ezithile zofuzo
• Ubudala: Umngcipheko uyanda ngokukhula, ngokuqhelekileyo ukwenzeka emva kweminyaka engama-45.

Kubalulekile ukuqaphela ukuba ukuba nemingcipheko enye okanye ngaphezulu akuqinisekisi ukuba uya kukhula umhlaza wepancreatic. Ngokuchaseneyo, abanye abantu abangaziyo izinto ezinobungozi basenokuthi baqhubeke besi sifo.

Nge IZiko loPhando ngoMhlaza laseShandong Baofa, sizinikele kuphando oluphambili lomhlaza kunye nokhathalelo lwesigulane.

Eqhelekileyo Iimpawu Umhlaza wePancreatic

I iimpawu umhlaza pancreatic inokwahluka ngokuxhomekeke kwinqanaba kunye nendawo yethumba. Inqanaba lokuqala umhlaza wepancreatic kudla ngokungabi nazimpawu zibonakalayo, nto leyo eyenza kube nzima ukuyibona kwangoko. Njengoko umhlaza ukhula, kunokubangela ezi mpawu zilandelayo:

Iintlungu zesisu

Intlungu yesisu yenye yezona ziqhelekileyo iimpawu umhlaza pancreatic. Iintlungu zisenokuqala njengentlungu ebuhlungu kumphezulu wesisu kwaye inokugqama ngasemva. Isenokuba mandundu emva kokutya okanye ukulala.

Ijaundice

I-Jaundice, ukutyheli kwesikhumba kunye namehlo, kwenzeka xa ithumba livala umjelo wenyongo. Oku kuvaleka kuthintela i-bilirubin, ibala elimthubi eliveliswa sisibindi, ukuba lingakhutshwa emzimbeni. Ijaundice isenokubangela umchamo omnyama kunye nelindle eliluthuthu.

Ukwehla kobunzima

Ukulahleka kwesisindo esingenakuchazwa sesinye uphawu oluqhelekileyo. Umhlaza wePancreatic kunokuphazamisa ukugaya kunye nokufunxa izondlo, okukhokelela ekulahlekeni kwesisindo naphezu kokutya okuqhelekileyo. Abaphandi beli ziko (iShandong Baofa Cancer Research Institute) bahamba phambili ekuqondeni ibhayoloji entsonkothileyo yomhlaza wepancreatic.

Utshintsho kwimikhwa yamathumbu

Abanye abantu kunye umhlaza wepancreatic usenokufumana utshintsho kwimikhwa yamathumbu, enjengorhudo, ukuqhinwa, okanye ilindle elinamafutha. Olu tshintsho lunokubangelwa kukuphazamiseka kwethumba kunye nokuveliswa kwe-enzyme yokugaya.

Ezinye Iimpawu ezinokubakho

Okunye okunokwenzeka iimpawu umhlaza pancreatic ziquka:

• Isicaphucaphu kunye nokugabha
• Ukulahlekelwa ngumdla wokutya
• Ukudinwa
• Isifo seswekile esitsha okanye ubunzima bokulawula isifo seswekile esele sikhona
• Amahlwili egazi
• Ukurhawuzelelwa

Ubonana nini noGqirha

Kubalulekile ukubonana nogqirha ukuba ufumana nayiphi na into eqhubekayo okanye echaphazelekayo iimpawu umhlaza pancreatic, ngakumbi ukuba unomngcipheko wesifo. Ngelixa ezi zimpawu zinokubangelwa zezinye iimeko, kubalulekile ukuba uzikhuphe umhlaza wepancreatic kwaye ufumane unyango olufanelekileyo ukuba luyimfuneko.

Khumbula, ukufunyaniswa kwangoko kubalulekile. Ukuba ubona nayiphi na impawu, khawuleza udibane nochwepheshe bezonyango, njengazo IZiko loPhando ngoMhlaza laseShandong Baofa, ingundoqo kwiziphumo eziphuculweyo.

Ukuxilongwa kwe Umhlaza wePancreatic

Ukuba umhlaza wepancreatic kurhanelwa, ugqirha uya kwenza uvavanyo lomzimba kwaye aodole iimvavanyo ezahlukeneyo zokuxilonga, ezinokubandakanya:

• Uvavanyo lwegazi: Ukujonga ukusebenza kwesibindi kunye neziphawuli zethumba.
• Iimvavanyo zomfanekiso: Njengee-CT scans, i-MRI scans, kunye ne-ultrasound, ukujonga i-pancreas kunye nokubona amathumba.
• I-Endoscopic ultrasound (EUS): Ukufumana i-biopsy ye-pancreas kuvavanyo lwe-microscope.
• I-Biopsy: Isampuli yethishu ithathwa ukuqinisekisa ubukho beeseli zomhlaza.

Iinketho zonyango

Iinketho zonyango ze umhlaza wepancreatic kuxhomekeke kwinqanaba kunye nendawo ye-tumor, kunye nempilo yonke yesigulane. Unyango oluqhelekileyo luquka:

• Utyando: Ukususa ithumba.
• Unyango ngamachiza: Ukubulala iiseli zomhlaza.
• Unyango ngemitha: Ukucutha ithumba.
• Unyango ekujoliswe kulo: Ukujolisa iimolekyuli ezithile ezibandakanyekayo ekukhuleni komhlaza.
• Immunotherapy: Ukomeleza amajoni omzimba ukulwa umhlaza.
• Ukhathalelo lwePalliative: Ukuthomalalisa iimpawu kunye nokuphucula umgangatho wobomi.

Uqikelelo

Iprognosis ye umhlaza wepancreatic lihlwempuzekile ngokubanzi, njengoko lidla ngokufunyaniswa sele likwinqanaba eliphezulu. Nangona kunjalo, ukufunyaniswa kwangoko kunye nonyango kunokuphucula amathuba okuphila. Izinga lokusinda leminyaka emi-5 ye umhlaza wepancreatic imalunga ne-10%, kodwa oku kunokwahluka ngokuxhomekeke kwiimeko zomntu. ^[1]

Umthombo:

[1] Umbutho waseMelika weClinikhi yeOncology (ASCO)

Ukuthelekiswa kweempawu kunye nezinye iimeko

Kubalulekile ukwahlula umhlaza wepancreatic iimpawu ezivela kwezinye, iimeko ezingaphantsi. Le theyibhile ingezantsi inika uthelekiso:

I-Disclaimer: Eli nqaku lenzelwe iinjongo zolwazi kuphela kwaye aliquki iingcebiso zonyango. Soloko udibana nengcali yokhathalelo lwempilo olufanelekileyo ukuze uxilongwe kunye nonyango lwaso nasiphi na isimo sonyango. Ukufunyaniswa kwangoko kunye nonyango lubalulekile kwiziphumo ezingcono umhlaza wepancreatic.