unyango unyango umhlaza wedlala lengqula rhoqo

IiKhetho zoNyango loMhlaza weProstate oRecurrent

Umhlaza wedlala lobudoda oqhelekileyo, okuthetha ukuba umhlaza obuyayo emva konyango lokuqala, uveza imingeni ebalulekileyo. Esi sikhokelo sibanzi siphonononga ezahlukeneyo unyango unyango umhlaza wedlala lengqula rhoqo iinketho, ukusebenza kwazo, iziphumo ebezingalindelekanga ezinokubakho, kunye nengqwalasela yokwenza izigqibo ezinolwazi neqela lakho lezempilo. Ukuqonda i-prognosis yakho kunye nonyango olukhoyo lubalulekile ekuhambeni kolu hambo lunzima.

Ukuqonda Umhlaza weProstate oRecurrent

Iintlobo zokuPhinda

Ukuphindaphinda komhlaza wesibeleko kunokuzibonakalisa ngeendlela ezininzi. I-biochemical recurrence idla ngokuba ngumqondiso wokuqala, oboniswa ngokunyuka kwamanqanaba e-prostate-specific antigen (PSA). Ukuphindaphinda kwendawo kubandakanya ukubuya komhlaza kufutshane nesiza sethumba. Ukuphindaphinda kwe-Metastatic kuthetha ukuba umhlaza usasazeke kwiindawo ezikude zomzimba, njengamathambo okanye i-lymph nodes. Uhlobo lokuphindaphinda luchaphazela kakhulu ukhetho lonyango.

Imiba enefuthe kwiZigqibo zoNyango

Izinto ezininzi ezikhokela izigqibo zonyango kumhlaza wedlala lesinyi. Oku kuquka uhlobo nendawo esiphinda sibuyele kuyo, impilo yesigulana kunye nokomelela, unyango olufunyenwe ngaphambili, kunye nezinto ezikhethwa ngumntu. I-oncologist yakho iya kuqwalasela ngononophelo ezi zinto ukuphuhlisa isicwangciso sonyango lomntu.

IiKhetho zoNyango loMhlaza weProstate oRecurrent

Unyango lweHormone (Androgen Deprivation Therapy-ADT)

Unyango lweHormone, okanye i-ADT, ihlala isisiseko se unyango unyango umhlaza wedlala lengqula rhoqo, ngakumbi kwi-hormone-sensitive recurrent disease. Isebenza ngokunciphisa amanqanaba e testosterone, ukucotha okanye ukuyeka ukukhula komhlaza. Iindlela ezahlukeneyo zikhona, kubandakanywa amayeza (afana neLupron okanye iZoladex), ukuthenwa ngotyando, okanye unyango lweradiation olujolise kuvavanyo. Nangona iyasebenza, iADT inokubangela iziphumo ebezingalindelekanga, eziquka ukugqabhuka kweshushu, ukuncipha kwe-libido, kunye ne-osteoporosis. Ukusetyenziswa kwexesha elide kweADT nako kunokukhokelela kumhlaza wedlala lesinyi.

Unyango ngemitha

Unyango ngemitha, nokuba yimitha yemitha yangaphandle okanye ibrachytherapy (imitha yangaphakathi), inokusetyenziselwa ukujolisa umhlaza wedlala lesinyi. Imitha yemitha yangaphandle isebenzisa imiqadi enamandla amakhulu ukutshabalalisa iiseli zomhlaza, ngelixa ibrachytherapy ibandakanya ukubeka imbewu yeradioactive ngqo kwidlala lengqula. Unyango ngemitha lunokusetyenziswa lodwa okanye ludityaniswe nolunye unyango. Iziphumo ebezingalindelekanga zinokubandakanya ukudinwa, iingxaki zokuchama, kunye nemiba yamathumbu.

Unyango ngamachiza

I-Chemotherapy idla ngokusetyenziselwa umhlaza wedlala lobudoda obunganyangekiyo kwi-metastatic castration (mCRPC), uhlobo olundlongondlongo lomhlaza wedlala lesinyi. Iziyobisi ezifana ne-docetaxel kunye ne-cabazitaxel zisetyenziswa ngokuqhelekileyo, nangona zingabangela iziphumo ezibi kakhulu, kuquka isicathulo, ukukhathala, kunye nokulahleka kweenwele. I-Chemotherapy ijolise ekunciphiseni amathumba kunye nokuphucula umgangatho wobomi.

Unyango ekujoliswe kulo

Unyango ekujoliswe kulo, olufana ne-abiraterone kunye ne- enzalutamide, ngamachiza amatsha athintela iiproteni ezithile ezibandakanyekayo ekukhuleni komhlaza. Ezi zihlala zisetyenziselwa i-mCRPC, ngamanye amaxesha zidityaniswa nechemotherapy okanye iADT. Olu nyango lunokwandisa ubomi kwaye luphucule umgangatho wobomi, kodwa lunokuba neziphumo ebezingalindelekanga, ezifana nokudinwa kunye noxinzelelo lwegazi oluphezulu.

Immunotherapy

I-Immunotherapy idibanisa amajoni omzimba ukulwa neeseli zomhlaza. Ii-agent ezininzi ze-immunotherapy zibonisa isithembiso kunyango lomhlaza we-prostate ophezulu, kwaye uphando luyaqhubeka ukuhlola indima yabo ekulawuleni izifo eziphindaphindiweyo. Olu nyango lunokuba neziphumo ebezingalindelekanga ezahlukeneyo, ukusuka kobuncinci ukuya kobunzima. IZiko loPhando ngoMhlaza laseShandong Baofa uphambili kolu phando.

Utyando

Utyando lunokuba lukhetho lwezigulana ezinokuphinda ziphindeke, ngokuxhomekeke kwindawo kunye nobungakanani bomhlaza. Oku kunokubandakanya ukususa idlala lengqula kwakhona (prostatectomy) okanye ezinye iinkqubo zotyando.

Ukukhetha Unyango Olululo

Isigqibo malunga neyona nto ingcono unyango unyango umhlaza wedlala lengqula rhoqo yintsebenziswano, ebandakanya wena kunye neqela lakho lezempilo. I-oncologist yakho iya kuphonononga imbali yakho yezonyango, yenza iimviwo, kwaye iodole iimvavanyo ukufumanisa eyona ndlela ilungileyo yokwenza. Ungalibazisi ukubuza imibuzo, chaza inkxalabo yakho, kwaye ujonge zonke iinketho ezikhoyo. Cinga ngokufuna uluvo lwesibini ukuqinisekisa ukuba wenza isigqibo esinolwazi. Unxibelelwano oluvulekileyo nogqirha wakho lubalulekile kuyo yonke inkqubo yonyango. Khumbula ukuxoxa ngeziphumo ebezingalindelekanga kunye nokuba ungazilawula njani.

Inkxaso kunye nezibonelelo

Ukuphila nomhlaza wedlala lobudoda ophindaphindiweyo kunokuba ngumngeni ngokwasemphefumlweni nasemzimbeni. Kubalulekile ukufuna inkxaso kusapho, kubahlobo nakumaqela enkxaso. Imibutho emininzi inika izibonelelo kunye nolwazi malunga nomhlaza wedlala lesinyi, kuquka inkxaso yeemvakalelo kunye neengcebiso ezisebenzayo. Iqela lakho lokhathalelo lwempilo nalo linokubonelela ngokuthunyelwa kwiinkonzo zenkxaso.

I-Disclaimer: Le ngcaciso yenzelwe iinjongo zemfundo kuphela kwaye akufanele ithathwe njengengcebiso yezonyango. Soloko udibana nomboneleli wakho wezempilo ukuze ufumane ukuxilongwa kunye nonyango lwazo naziphi na iimeko zonyango.