unyango i-squamous non small cell umhlaza wemiphunga unyango

Unyango lweSquamous Non-Small Cell Lung Cancer

Esi sikhokelo sibanzi siphonononga iindlela ezahlukeneyo zonyango ezikhoyo kumhlaza wemiphunga we-squamous ongeyonxalenye encinci (NSCLC). Sijonge kwinkqubela phambili yamva nje unyango, kubandakanywa utyando, i-chemotherapy, unyango lwe-radiation, unyango olujoliswe kuyo, kunye ne-immunotherapy, enika ukuqonda okucacileyo kwendlela yokusebenza kunye nemiphumo enokubakho. Funda malunga nesiteji, ukuxilongwa, kunye nokubaluleka kokwenziwa komntu unyango izicwangciso zokulawula esi sifo sinzima. Sikwajongana nemilinganiselo yokunyamekela yokuxhasa ukuphucula umgangatho wobomi ngexesha nasemva unyango.

Ukuqonda i-squamous engeyiyo iSeli encinci yoMhlaza weMiphunga

Yintoni uMhlaza weSquamous Cell Lung?

I-squamous cell carcinoma luhlobo lwe NSCLC eqala kulwelo lweendlela zomoya ezinkulu emiphungeni. Idla ngokunxulunyaniswa nembali yokutshaya. Ukufunyaniswa kwangethuba kubalulekile ukuze uphumelele unyango. I unyango indlela ixhomekeke kakhulu kumntu ngamnye kwaye ixhomekeke kwinqanaba lomhlaza kunye nempilo yonke yesigulana.

IStaging Squamous Non-Small Cell Lung Cancer

Ukuma kweqonga kubandakanya ukujonga ubungakanani bokunwenwa komhlaza. Oku kubalulekile ekumiseleni eyona ndlela ilungileyo unyango ngenxa squamous non-mncinci umhlaza wemiphunga weseli. Ukulinganisa ngokuqhelekileyo kwenziwa ngovavanyo lokucinga (i-CT scans, i-PET scans), i-biopsies, kunye ne-bronchoscopy. Inqanaba (I-IV) lichaphazela unyango izigqibo, kwaye izigulane ziyakhuthazwa ukuba zixoxe ngokuthe ngqo ngoxilongo lwabo kunye neqonga kunye ne-oncologist yabo. Ukuqonda inqanaba lakho kuya kukuvumela ukuba ucwangcise ngentsebenziswano eyona ifanelekileyo unyango iqhinga.

IiKhetho Zonyango kwiSquamous Non-Small Cell Lung Cancer

Utyando

Utyando ludla ngokuba ngoyena uphambili unyango ukhetho lwenqanaba lokuqala squamous non-mncinci umhlaza wemiphunga weseli. Ngokuxhomekeke kwindawo kunye nobukhulu be-tumor, iinkqubo ezahlukeneyo zotyando zinokusetyenziswa. Oku kunokubandakanya ukususa ithumba kunye nenxalenye yezicubu zemiphunga ezijikelezileyo (i-lobectomy okanye i-wedge resection). Ukuba nokwenzeka kotyando kuxhomekeke kwizinto ezahlukeneyo ezifana nempilo jikelele yesigulana kunye nendawo kunye nobukhulu bethumba.

Unyango ngamachiza

Unyango ngamachiza lubandakanya ukusebenzisa amayeza okubulala iiseli zomhlaza. Ihlala isetyenziswa ngokudibeneyo nezinye unyango iindlela, ezifana nonyango ngemitha okanye utyando, kumanqanaba aphezulu ngakumbi squamous non-mncinci umhlaza wemiphunga weseli. Amachiza aqhelekileyo echemotherapy asetyenziselwa NSCLC ziquka i-cisplatin, i-carboplatin, kunye ne-paclitaxel. Iziphumo ebezingalindelekanga ziyahluka, kwaye ukulawula oku kungumba obalulekileyo we unyango inkqubo.

Unyango ngemitha

Unyango ngemitha lusebenzisa imitha yemitha ephezulu ukonakalisa nokutshabalalisa iiseli zomhlaza. Ingasetyenziswa phambi kotyando ukuthoba amathumba (unyango lwe-neoadjuvant), emva kotyando ukuphelisa naziphi na iiseli zomhlaza eziseleyo (unyango lwe-adjuvant), okanye njengonyango lokuqala. unyango kwizigulane ezingafanelanga utyando. Unyango ngemitha lusenokusetyenziswa ukulawula iimpawu ezibangelwa ngumhlaza ophezulu.

Unyango ekujoliswe kulo

Unyango ekujoliswe kulo lusebenzisa amachiza ajolise ngokukodwa kwiiseli zomhlaza ezinotshintsho oluthile lwemfuza. Le ndlela inokusebenza kakhulu kwizigulana ezinamathumba anotshintsho oluthile lwemfuzo. Ngokomzekelo, ezinye iinguqu ze-EGFR kwi NSCLC inokusabela kakuhle kunyango olujoliswe kuyo. Uvavanyo lwemfuzo lubalulekile ukumisela ukufaneleka kolu nyango.

Immunotherapy

I-Immunotherapy ibamba amandla amajoni omzimba okulwa iiseli zomhlaza. Olu nyango lusebenza ngokuvuselela okanye ukunyusa izinga lokuzikhusela komzimba ekuhlaseleni nasekutshabalaliseni iiseli zomhlaza. Immunotherapy iye yatshintsha indlela unyango zomhlaza ezininzi, kuquka ezinye iintlobo NSCLC. Ii-checkpoints inhibitors ngumzekelo omkhulu wolu hlobo unyango.

Ukhathalelo lweNkxaso

Ukulawula iziphumo ebezingalindelekanga zomhlaza unyango yinxalenye ebalulekileyo yokhathalelo jikelele. Ukhathalelo oluxhasayo lubandakanya uluhlu olubanzi lweenkonzo, kubandakanya ulawulo lweentlungu, inkxaso yesondlo, kunye neengcebiso, ukuphucula umgangatho wobomi besigulane ngexesha nasemva. unyango. Iingxoxo kunye ne-oncologist yakho kunye neqela labo lokhathalelo zibalulekile ekumiseleni isicwangciso sononophelo esixhasayo.

IziCwangciso zoNyango ezenzelwe wena

Kubalulekile ukukhumbula oko unyango ngenxa squamous non-mncinci umhlaza wemiphunga weseli yenzelwe umntu kakhulu. Eyona ndlela ilungileyo ixhomekeke kwizinto ezininzi ezibandakanya inqanaba lomhlaza, impilo yesigulana iyonke, kunye nobukho balo naluphi na utshintsho oluthile lwemfuzo. Ingxoxo ebanzi kunye ne-oncologist ibalulekile ekuphuhliseni ukulungelelanisa unyango isicwangciso esandisa ukusebenza kakuhle ngelixa sinciphisa iziphumo ebezingalindelekanga. Iqela lakho lezempilo liya kusebenza nawe ukwenza isicwangciso esihlangabezana neemfuno kunye neenjongo zakho.

Ngolwazi oluthe kratya okanye ukwenza ishedyuli yokubonisana, nceda undwendwele IZiko loPhando ngoMhlaza laseShandong Baofa. Le ngcaciso yenzelwe iinjongo zemfundo kuphela kwaye akufanele ithathwe njengengcebiso yezonyango. Soloko udibana nengcali yezempilo kuyo nayiphi na inkxalabo yezempilo okanye ngaphambi kokuba wenze naziphi na izigqibo ezinxulumene nempilo yakho okanye unyango.