Chothandizira chathu chachikulu ndikuti chithandizo chamankhwala chokhazikika chimagwirizanitsa ubwino wa chemotherapy ndi immunotherapy, ndipo kwa nthawi yoyamba, awiriwa aphatikizidwa ndikugwiritsidwa ntchito ku intratumoral therapy kupyolera mwa kuchitapo kanthu. Imaphatikiza chithandizo chapadziko lonse lapansi komanso chapadziko lonse lapansi, ndikuwonjezera kuchuluka kwamankhwala ndi nthawi yamankhwala kudzera pakutulutsa kwanthawi zonse kwamankhwala mkati mwa chotupacho, chomwe sichimangogwira ntchito yoletsa khansa ya m'dera la chemotherapy, komanso imaganiziranso ntchito ya systemic immunotherapy, potero imapanga zofooka za njira zina zochiritsira, kupereka malingaliro ndi njira zatsopano zochizira khansa, makamaka zotupa zapakati komanso zapamwamba, makamaka pochepetsa kufunikira kwa chotupa; Chithandizo cha UMPIC chili ndi mwayi wogwiritsa ntchito chotupa ngati gwero la antigen komanso katemera wa autologous, zomwe zimagwirizananso ndi kakulidwe ka Personalized Medicine. Ndipo amagwiritsidwa ntchito ku chipatala, hapten pamodzi ndi mankhwala a chemotherapy kuti apitirize kumasulidwa kwa khansa ya pancreatic, pamene imayambitsa zotsatira za distal, zomwe zimachititsa kuti chitetezo cha mthupi chitetezeke, T-cell zokhudzana ndi CD4, CD8, DC, T ndi NK maselo, ndi B-maselo okhudzana ndi chotupa autoantibodies: Antibodies to P53, P16, Cmy2c, Survey, HCC ndi ma oncogenes ena, aka ndi nthawi yoyamba kupeza kuti T ndi B akukhudzidwa ndi kuyankha kwa chitetezo cha mthupi, ndi ntchito zachipatala za zotsatira za distal ndi chithandizo ichi chinasankhidwa kuti "Clinical Operation Guidelines for Interventional Treatment of Advanced Pancreatic Cancer" (Mayesero) (7th edition) yopangidwa ndi Chinese Anti-Cancer Association, National Clinical Medical Research Center ndi National Clinical Research Center yofalitsidwa ndi National Clinical Medical Research and Interrapy Alliance yofalitsidwa. pa Journal of Clinical Radiology, voliyumu 43, nambala 19, 2024, 1636-1648.