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Qala hape
Baofa Yu, M.D. Ngaka e ka Sehloohong Chaena, Moprofesa oa Motlatsi oa Univesithi ea Texas (El Paso) (2016) le Moprofesa oa Motlatsi oa Univesithi ea Bophirimela ea Saense ea Bophelo (2016). O ile a qeta Peking Union Medical College (Peking Union Medical College) ka 1988. E ne e le molekane oa morao-rao ho UCSD ho tloha 1990 ho ea 1991, Salk ho tloha 1992 ho ea 1993, Motlatsi oa Motlatsi oa Moprofesa, UCSD ho tloha 1994 ho ea ho 1998. United States e ne e le motho ea sebetsanang le kankere ea lithethefatsi le litlhare tsa kankere ea likokoana-hloko. O ile a qapa khopolo e ncha ea ho sebelisa lisele tsa hlahala e le mokhoa o tsitsitseng oa ho lokolloa ha lithethefatsi tse thibelang kankere le mokhoa oa phekolo oa polokelo e tsitsitseng ea ho lokolloa, e nang le boleng ba kopo ea bongaka, e boetse e bitsoa ultro-Minimum incision personalized intratumoral chemoimmunotherapy (UMIPIC). Ka 1998, o ile a khutlela Chaena 'me a theha Setsi sa Lipatlisiso sa Shandong Baofa le Sepetlele sa Kankere sa Taimei Baofa sebakeng sa mahaeng sa Dongping ka lichelete tsa theknoloji,' me a sebeletsa e le molula-setulo oa Shandong Baofa Cancer Treatment Co., LTD., 'me hamorao a theha Jinan Baofa Cancer Hospital (2004). Sepetlele sa Kankere sa Dongping Baofa (2011), Sepetlele sa Kankere sa Beijing Baofa (2013) le Immuno Oncology Systems, Inc. UMIPIC ena e bolokehile, e sebetsa habonolo, ebile e ka ikatisa ka molemo o motle bakeng sa hlahala eohle e tiileng. Kajeno phekolo ena e amoheloa ho "Litaelo tsa Ts'ebetso ea Kliniki bakeng sa Phekolo ea Phano ea Kankere e Tsoetseng Pele ea Pancreatic" (Trial) (khatiso ea 7), e kopantsoeng ke Mokhatlo oa Chaena oa Anti-Cancer, National Clinical Medical Research Center bakeng sa Radiology le Therapy, le National Interventional Medicine Innovation Alliance, Journal of Clinical Radiology, volume 43, 162 nomoro ea 163.
O hatisitse lipampiri tse fetang 60 mabapi le phekolo ena ho Tlhaho: Tlaleho ea Saense, Journal of Cancer, J Basic Clin Pharma, J Immunological Sci, Japanese Journal of Gastroenterology and Hepatology, Novel Approaches in Cancer Study, Academic Journal of Engineering Studies, Nov Res Sci, Journal of Hepatocellular carcinoma, Leqephe la Likokoana-hloko tsa Likokoana-hloko, Lipatlisiso tsa Likokoana-hloko tsa Likokoana-hloko, Liphatsa tsa lefutso tsa Sechaena ea Chest, Proc.Natl.Acad.Sci.USA, Pancreas le likoranta tse ling le lipampiri tse ngata tsa poso li nkile karolo kopanong ea AACR le ASCO.
Tlatsetso ea rona e kholo ke hore phekolo ea nako e telele ea ho lokolloa e kopanya melemo ea chemotherapy le immunotherapy, 'me ka lekhetlo la pele, tse peli li kopantsoe le ho sebelisoa ho phekolo ea intratumoral ka ho kenella. E kopanya kalafo ea lehae le ea lefats'e, 'me e eketsa khatello ea maikutlo le nako ea ts'ebetso ea lithethefatsi ka ho lokolloa ha lithethefatsi ka har'a hlahala, e sa bapaleng feela phello ea anticancer ea lehae ea lithethefatsi tsa chemotherapy, empa hape e ela hloko karolo ea systemic immunotherapy, ka hona e etsa mefokolo ea liphekolo tse ling, e fana ka mehopolo le mekhoa e mecha ea kalafo ea mofets'e, haholo-holo bakeng sa lihlahala tse bohareng le tse tsoetseng pele, haholoholo bakeng sa ho fokotsa boleng ba ho fetisoa ha hlahala. Phekolo ea UMPIC e na le molemo oa ho sebelisa hlahala joalo ka mohloli oa antigen le ente ea autologous, e leng hape e tsamaellanang le mokhoa oa nts'etsopele oa Moriana oa Motho. 'Me e sebelisoa tleliniking, hapten e kopantsoe le lithethefatsi tsa chemotherapy bakeng sa phekolo e tsoelang pele ea phekolo ea kankere ea pancreatic, ha e ntse e etsa hore ho be le phello ea distal, eo mohloli oa eona e leng ho susumetsa karabelo ea 'mele ea ho itšireletsa mafung, lisele tsa T-cell tse amanang le CD4, CD8, DC, T le NK tse amanang le B-cell tse amanang le tumor autoantibodies: Antibodies ho P53, P16, Cmyc2MP, HCC le li-oncogenes tse ling, lena ke lekhetlo la pele ho fumana hore T le B li ameha karabelong ea 'mele ea ho itšireletsa mafung,' me mesebetsi ea kliniki ea phello ea distal le phekolo ena e ile ea khethoa bakeng sa "Litaelo tsa Ts'ebetso ea Kliniki bakeng sa Phekolo ea Ts'ebetso ea Kankere e Phahameng ea Pancreatic" (Trial) (khatiso ea 7) e kopantsoeng ke Mokhatlo oa Chaena oa Anti-Cancer, National Clinical Medical Research Centre e phatlalalitsoeng ke Mokhatlo oa Sechaba oa Lipatlisiso le Bongaka ba Sechaba. ho Journal of Clinical Radiology, volume 43, number 19, 2024, 1636-1648.
Litšupiso:
| Selemo | Sehlooho sa Sengoloa | Khatiso |
| 2015 | Phello e matlafalitsoeng ea Hapten methating e tsoetseng pele ea mofetše oa matšoafo ka ultra-minimum incision personalized intratumoral. | Kankere ea Matšoafo: Sepheo le Therapy, 2015; 6 1-11 |
| 2015 | Ho sireletsa se tloaelehileng molemong oa ho bolaea mofetše | 2015 Bangoli. Cancer Medicine e hatisitsoeng ke John Wiley & Sons Ltd.1349-1403 |
| 2015 | Mefokolo le Likotsi Tsa ho Sebelisa Litoeba le Likhoto Lithutong tsa Chemoprevention ea Kankere | Journal of Cancer 2015;6(10): 1058-1065.doi: 10.7150/jca.12519 |
| 2015 | Nako ea ho pholoha e ntlafalitsoeng ea Hapten ho e tsoetseng pele ea hepatocellular carcinoma ka ultra-minimum incision personalized intratumoral chemoimmunotherapy. | Journal of Hepatocellular Carcinoma, 2015: 2,1-12 |
| 2015 | Tšebeliso ea hapten e kopantsoeng le lithethefatsi tsa Catatonic bakeng sa Ntlafatso ea Phello ea Phekolo Mehatong e Tsoetseng Pele ea Kankere ea Pancreatic | Journal of Lipatlisiso tsa Sebete, Mathata & Therapy, 2015,1(3):013-23 |
| 2016 | Ho Ithuta ka Bohlokoa ba Thibelo ea Phetoho ho Tsoa Kankere e Phekolehang le Lihlahala Tse Benign | Journal of Cancer 2016; 7(4): 436-445. doi: 10.7150/jca.13832 |
| 2016 | Hapten e Ntlafalitse Molemo oa ho Pholoha ka Kakaretso Mehatong ea Morao-rao ea Kankere e sa Nyenyane ea Matšoafo ea Cell (NSCLC) ka Ultra-Minimum Incision Personalized Intratumoral Chemo Immunotherapy (UMIPIC) Therapy With and without Radiation Therapy Submit Manuscript | Journal of Cancer Prevention & Current Research 2016, 4(2): 00116 |
| 2020 | Mokhoa oa Novel Eclectic bakeng sa Therapy ea Mofets'e ka Liquid Knife & Immuno Therapy: UMIPIC, e kanna ea feta Opereishene e ngata, Chemotherapy le Therapy ea Radiation bakeng sa Methati eohle ea Tumor e Tiileng. | Mehato e Ncha ea Thuto ea Kankere NACS.000590. 4(3).2020 |
| 2020 | Lithethefatsi tse kopantsoeng ke H2O2 Injection Intratumoral ho fetola Matrix ea Extracellular hore e be Autologous Coagulum joalo ka Depot ea Lithethefatsi. | Lipatlisiso tsa Novel in Sciences NRS.000584. 4(2).2020 |
| 2020 | Tšepo e Ncha ea Phekolo ea Kankere ka Liquid Knife & Immuno Therapy: UMIPIC | Mekhoa ea Hona Joale ho Clinical & Medical Sciences ISSN:2689-4246 Letsatsi la Phatlalatso: 20 Hlakubele 2020 |
| 2022 | Acute Tumor Inflammation e nang le CD4/8+ le CD11+ e Matlafalitsoeng ke Nako ea Nako e Telele ea ho Pholoha Mehatong e Tsoetseng Pele ea lihlahala tse tiileng ka Ultra Minimum Incision Personalized Intratumoral Chemoimmunotehrapy. | Journal ea Japane ea Gastroenterology le Hepatology |
| 2022 | Ho ruruha ho Acute ka Ponahalo e Khethehileng ea CD11 & CD4 ho Hlahisa Phello ea Abscopal ka Intramoral Injection Chemotherapy Drug e nang le Hapten ho Mohlala oa liphoofolo. | Journal of Immunological Sciences |
| 2022 | Nako e Ncha ea Opereishene ea Immuno ea Tla: Mokhoa oa Novel Eclectic bakeng sa Phekolo ea Mofetše ka Liquid Knife & Immuno Therapy. | Journal ea Academic ea Lithuto tsa Boenjiniere |
| 2022 | Acute Tumor Inflammation e nang le CD4 / 8 + le CD11 + E lelefatsa Phello ea ho Pholoha e Bakiloeng ke Intratumral Injection Optimum Combination of Chemotherapy Drugs le Hydralazine e le Hapten ka Mohlala oa Liphoofolo. | Journal ea Japane ea Gastroenterology le Hepatology |
| 2023 | Tsosa Lisele tsa 'mele oa ho itšireletsa mafung ka Hapten e Matlafalitsoeng ka Intratumoral Chemotherapy ka Penicillin Prolong Pancreatic Cancer Survival. | Journal of Cancer 2023; 14(8): 1282-1292 |
| 2023 | Ho lebela ka katleho sebakeng sa antigen ea nyutlelie ea oncogenic ka tumor e amanang le li-autoantibodies (iTAA) | potefolio ea tlhaho Scientific Reports volume 13, Nomoro ea sehlooho: 9902 (2023) |
| 2023 | Liphetoho tsa 'mele oa ho itšireletsa mafung tse bakoang ke Intratumoral Hapten Plus Chemotherapy Lithethefatsi tsa EndometrialCancer. | Journal of Basic and Clinical Pharmacy July 31,2023. DOI: 10.37532/0976-0113.14(S1).17 |
| 2023 | Tokisetso ea Kankere ea Immunotherapy le Ts'ebetso ea Lisele tsa 'mele ka Hapten-Enhanced Chemotherapy ho Kankere ea Matšoafo ea Matšoafo. | Journal of Basic and Clinical Pharmacy August 11, 2023. DOI: 10.37532/0976-0113.14(S1).18 |
| 2023 | Tlhahlobo ea scRNA-Seq Liphetoho tsa 'mele oa Intratumoral Hapten Plus Chemotherapy Lithethefatsi bakeng sa Phekolo ea Kankere ea Matsoele ea Banna. | JORAL OF CANCER SAENSE LE CLINICAL THERAPEUTICS November 27, 2023. DOI:10.26502/jcsct.5079214 |
| 2024 | Phello ea sodium stibogluconate ho bokella le ho tsosa lisele tsa 'mele tsa ho itšireletsa mafung ka har'a mokelikeli oa pleural oa mofets'e oa pancreatic bakeng sa immunotherapy. | Frontiers in Immunology January 19, 2024. DOI:10.3389/fimmu.2023.1315468 |
| 2024 | Hapten-Mediated Chemical Immune Therapy ka Tsamaiso ea Lithethefatsi ho Kankere ea Molomo ntle le Hysterectomy | Journal of Surgery June 13, 2024. DOI:10.29011/2575-9760.11063 |
| 2024 | Sebelisa scRNA-Seq Profile ho Hlalosa Immunologic Response after Intra-tumor Hapen Enhanced Chemotherapy Tabeng ea Intracranial Anaplastic Hemangiopericytoma Liver Metastasis: Tlaleho ea Nyeoe | Journal of Surgery June 10, 2024. DOI:10.29011/2575-9760.11063 |
