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Baofa Yu, MD Chiremba Mukuru muChina, Adjunct Purofesa paYunivhesiti yeTexas (El Paso) (2016) uye Adjunct Purofesa paWestern University of Health Sciences (2016). Akapedza kudzidza kubva kuPeking Union Medical College (Peking Union Medical College) muna 1988. Aive post-doctoral shamwari kuUCSD kubva 1990 kusvika 1991, Salk kubva 1992 kusvika 1993, Assistant Adjunct Professor, UCSD kubva 1994 kusvika 1998. MuUnited States cular mutakuri wezvinodhaka zvinodhaka uye ainyanya kutsvagisa gomarara remishonga. Akagadzira iyo pfungwa nyowani yekushandisa bundu tishu seyakasimba kuburitsa sisitimu yemishonga inorwisa cancer uye nzira yekurapa yekusimbisa kuburitsa reservoir, ine kiriniki yekushandisa kukosha, inonzi zvakare ultro-Minimum incision personalized intratumoral chemoimmunotherapy (UMIPIC). Muna 1998, akadzokera kuChina uye akatanga Shandong Baofa Research Institute uye Taimei Baofa Cancer Hospital munzvimbo yeDongping yekumaruwa ine mari yetekinoroji, uye akashanda sasachigaro weShandong Baofa Cancer Treatment Co., LTD., uye akazogadzira Jinan Baofa Cancer Hospital (2004). Dongping Baofa General Hospital (2011), Beijing Baofa Cancer Hospital (2013) uye Immuno Oncology Systems, Inc. UMIPIC iyi yakachengeteka, iri nyore kushanda, uye inoberekana nerubatsiro rwakanaka kune ese akasimba bundu. Nhasi kurapa uku kunogamuchirwa ku "Clinical Operation Guidelines for Interventional Treatment of Advanced Pancreatic Cancer" (Trial) (7th edition), yakabatanidzwa neChinese Anti-Cancer Association, National Clinical Medical Research Center yeRadiology uye Therapy, uye National Interventional Medicine Innovation Alliance, Journal of Clinical Radiology, vhoriyamu 94, 63, 63 nhamba 162.

Akabudisa mapepa anopfuura makumi matanhatu pamusoro pekurapa uku muNature: Scientific Report, Journal of Cancer, J Basic Clin Pharma, J Immunological Sci, Japanese Journal yeGastroenterology uye Hepatology, Novel Approaches muCancer Study, Academic Journal of Engineering Studies, Nov Res Sci, Journal of Hepatocellular carcinoma, The lung Journal of Researching, Chinea yeChest,Proc.Natl.Acad.Sci.USA, Pancreas nemamwe majenari uye akawanda mapepa ekutumira akatora chikamu mumusangano weAACR neASCO.

Mupiro wedu mukuru ndewekuti kurapa-kusunungurwa kwakasimba kunobatanidza zvakanakira chemotherapy uye immunotherapy, uye kekutanga, maviri acho akabatanidzwa uye anoshandiswa kune intratumoral therapy kuburikidza nekupindira. Inobatanidza kurapa kwemuno neyepasirese, uye inowedzera kusungirirwa uye nguva yekushandiswa kwezvinodhaka kuburikidza nekuburitswa kwakasimba kwezvinodhaka mukati mebundu, iro risingangoite yemuno anticancer mhedzisiro yechemotherapy mishonga, asi zvakare inofunga nezve basa resystemic immunotherapy, nekudaro kugadzira kukanganisa kwemamwe marapirwo, ichipa mazano matsva uye nzira dzekurapwa kwegomarara, kunyanya kumamota epakati uye epamusoro, kunyanya kudzikisa bundu rakakosha kudzoka. UMPIC kurapa ine mukana wekushandisa bundu seantigen sosi uye autologous vaccine, iyo inofambirana nemaitiro ekusimudzira eMushonga Wemunhu. Uye inoshandiswa kukiriniki, hapten yakasanganiswa nemishonga yechemotherapy yekuenderera mberi kusunungurwa kurapwa kwepancreatic cancer primary focus, uku ichikonzera distal effect, musimboti wayo ndeyekuunza immune system, T-cell-inoenderana CD4, CD8, DC, T uye NK masero, uye B-cell-inoenderana nebundu autoantibodies: Antibodies kuP53, P16, Cmy2c, 6MP, HCC, Ivivic, HCC uye mamwe oncogenes, ino inguva yekutanga kuwana kuti T uye B vanobatanidzwa mukupindura kwemuviri, uye mabasa ekiriniki eiyo distal mhedzisiro uye kurapa uku kwakasarudzirwa "Clinical Operation Guidelines for Interventional Treatment of Advanced Pancreatic Cancer" (Trial) (7th edition) yakaitwa pamwe chete neChinese Anti-Cancer Association, National Clinical Medical Research uye National Clinical Research Center yakadhindwa. pa Journal of Clinical Radiology, vhoriyamu 43, nhamba 19, 2024, 1636-1648.

References:

Gore	Musoro weChinyorwa	Publication
2015	Hapten-enhanced therapeutic effect mumatanho epamusoro ekenza yemapapu ne-ultra-minimum incision personalized intratumoral.	Kenza yemapapu: Target uye Therapy, 2015; 6 1-11
2015	Kuchengetedza zvakajairika kuitira kuuraya cancer zvirinani	2015 Vanyori. Cancer Medicine yakabudiswa naJohn Wiley & Sons Ltd.1349-1403
2015	Kushaya simba uye Njodzi dzeKushandisa Mice nemakonzo muCancer Chemoprevention Studies	Nyaya yeCancer 2015;6(10): 1058-1065.doi: 10.7150/jca.12519
2015	Hapten-yakawedzera nguva yekupona muyakanyanya hepatocellular carcinoma ne Ultra-minimum incision yakasarudzika intratumoral chemoimmunotherapy.	Nyaya yeHepatocellular Carcinoma, 2015: 2, 1-12
2015	Kushandiswa kwehapten yakasanganiswa Catatonic mishonga yeKusimudzira Therapeutic Effect muAdvanced Stages yePancreatic Cancer.	Chinyorwa cheLiver Research, Disorders & Therapy, 2015,1(3):013-23
2016	Kudzidza nezve Kukosha kweMutation Dziviriro kubva Kunorapika Cancers uye Benign Tumors	Nyaya yeCancer 2016; 7(4): 436-445. doi: 10.7150/jca.13832
2016	Hapten Yakavandudzwa Yese Yekupona Benefit muMatanho Ekupedzisira eIsiri-Idiki Cell Lung Cancer (NSCLC) neUltra-Minimum Incision Personalized Intratumoral Chemo Immunotherapy (UMIPIC) Therapy Ine uye isina Radiation Therapy Tumira Manuscript.	Nyaya yeCancer Prevention & Current Research 2016, 4 (2): 00116
2020	Iyo Novel Eclectic Nzira yeCancer Therapy ine Liquid Knife & Immuno Therapy: UMIPIC, inogona Kupfuura Kuvhiya kwakawanda, Chemotherapy uye Radiation Therapy kune ese Matanho eSolid Tumor.	Novel Approaches muCancer Study NACS.000590. 4(3).2020
2020	Mushonga Wakasanganiswa neH2O2 Jekiseni Intratumoral kushandura Extracellular Matrix kuita Autologous Coagulum seDhipatimendi rezvinodhaka.	Novel Research muSainzi NRS.000584. 4(2).2020
2020	Tariro Itsva yeCancer Therapy neLiquid Knife & Immuno Therapy: UMIPIC	Azvino Mafambiro muClinical & Medical Sayenzi ISSN:2689-4246 Zuva Rakabudiswa: Kurume 20, 2020
2022	Acute Tumor Inflammation ine CD4/8+ uye CD11+ Yakakwidziridzwa Yenguva Yekupona Kwenguva muMatanho ePamusoro eese Solid tumors neUltra Minimum Incision Personalized Intratumoral Chemoimmunotehrapy.	Japanese Journal yeGastroenterology uye Hepatology
2022	Acute Inflammation ine Special Expression yeCD11 & CD4 Inoburitsa Abscopal Effect neIntramoral Injection Chemotherapy Mushonga une Hapten muMhuka Model.	Nyaya yeImmunological Sayenzi
2022	A New Era yeImmuno Surgery iri Kuuya: Iyo Novel Eclectic Nzira Yekurapa Kenza neLiquid Knife & Immuno Therapy.	Academic Journal yeInjiniya Zvidzidzo
2022	Acute Tumor Inflammation neCD4/8+ uye CD11+ Rebesa The Survival Effect Induced by Intratumral Injection Optimum Combination of Chemotherapy Drugs with Hydralazine as Hapten in Animal Model.	Japanese Journal yeGastroenterology uye Hepatology
2023	Awaken Immune Cells naHapten Enhanced Intratumoral Chemotherapy nePenicillin Prolong Pancreatic Cancer Survival.	Nyaya yeCancer 2023; 14(8): 1282-1292
2023	Kubudirira kunanga mune situ ye oncogenic nuclear antigen nehapten induced bundu rinobatanidza autoantibodies (iTAA)	nature portfolio Scientific Reports volume 13, Chinyorwa nhamba: 9902 (2023)
2023	Shanduko dzeImmune Dzinokonzereswa neIntratumoral Hapten Plus Chemotherapy Mishonga yeEndometrialCancer.	Chinyorwa cheBasic uye Clinical Pharmacy Chikunguru 31,2023. DOI: 10.37532/0976-0113.14(S1).17
2023	Cancer Immunotherapy Kugadzirira uye Immune Cells Activation kuburikidza neHapten-Enhanced Chemotherapy muPrimary Lung Cancer.	Journal of Basic uye Clinical Pharmacy Nyamavhuvhu 11, 2023. DOI: 10.37532/0976-0113.14(S1).18
2023	scRNA-Seq Analysis Kuchinja Kwekudzivirira Kwemuviri kweIntratumoral Hapten Plus Chemotherapy Mishonga yeKurapa Kenza yeMazamu	JOURNAL OF CANCER SCIENCE AND CLINICAL THERAPEUTICS November 27, 2023. DOI:10.26502/jcsct.5079214
2024	Mhedzisiro yesodium stibogluconate mukutora uye kumutsa masero edziviriro mu pleural fluid yepancreatic cancer kugadzirira immunotherapy.	Frontiers in Immunology Ndira 19, 2024. DOI:10.3389/fimmu.2023.1315468
2024	Hapten-Mediated Chemical Immune Therapy neDrug Administration muCervical Cancer pasina Hysterectomy	Nyaya Yekuvhiya Chikumi 13, 2024. DOI:10.29011/2575-9760.11063
2024	Shandisa scRNA-Seq Profile kutsanangura Immunologic Response mushure meIntra-tumor Hapen Enhanced Chemotherapy paNyaya yeIntracranial Anaplastic Hemangiopericytoma Liver Metastasis: Nyaya Yenyaya.	Journal of Surgery June 10, 2024. DOI:10.29011/2575-9760.11063

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