Ukuqonda ukuhlolwa komdlavuza we-pancreatic: umhlahlandlela ophelele 

Ukuhlolwa komdlavuza we-pancreatic zibalulekile ukuthola ukutholwa kwangaphambi kokuthola nokuxilongwa kwalesi sifo esinzima. Ukukhethwa kokufanele ukuhlolwa Kuya ngezici zobungozi ngazinye, izimpawu, kanye nesigaba somdlavuza ongaba khona. Lo mhlahlandlela uhlinzeka ngesibukezo sabahlukahlukene Ukuhlolwa komdlavuza we-pancreatic, izinhloso zabo, nokuthi yini okufanele bayilindele.

Kungani Ukuhlolwa komdlavuza we-pancreatic Kubalulekile?

Umdlavuza we-pancreatic Kuvame ukutholakala esiteji sekwephuzile ngoba izimpawu zakuqala zingaba yiphutha futhi zinephutha kalula kwezinye izimo. Lokhu kuxilongwa sekwedlule isikhathi kuthinta kakhulu izinketho zokwelashwa kanye nokuqanjwa kwe-prognosis. Ngakho-ke, ukuqonda kuyatholakala Ukuhlolwa komdlavuza we-pancreatic Futhi lapho kungadingeka khona kubalulekile ekuphathweni kwezempilo okusebenzayo.

Obani okufanele bacabangele Ukuhlolwa komdlavuza we-pancreatic?

Ngenkathi inqubo ejwayelekile ye umdlavuza we-pancreatic Akunconyelwe kakhulu inani labantu, abantu abathile abanezici ezikhuphukayo ezikhulayo kufanele baxoxe ngezinketho zokuhlola nabahlinzeki babo bezempilo. Izici zobungozi zifaka:

• Umlando womndeni wa umdlavuza we-pancreatic
• Amanye ama-shintsho wofuzo, njenge-brca1 / 2 izilonda, i-peutz-jeggys syndrome, i-lynch syndrome, kanye ne-atypical atypical Multiple Melanoma (FAMMM) Syndrome
• I-pancreatitis engapheli
• Isifo sikashukela (ikakhulukazi isifo sikashukela esisha kubantu abadala asebekhulile)
• Ukukhuluphala
• Ukubhema

Izinhlobo ze Ukuhlolwa komdlavuza we-pancreatic

Okuhlukahlukene okuhlukile ukuhlolwa ingasetshenziswa ukusiza ukuthola umdlavuza we-pancreatic. Lezi ukuhlolwa ingahlukaniswa kabanzi ekulingisweni ukuhlolwa, igazi ukuhlolwa, nezinqubo ze-biopsy.

Ukuhlolwa kokucabanga

Into eminga ukuhlolwa Nikeza izethulo ezibukwayo zamanyikwe kanye nezitho ezizungezile, ukusiza odokotela bakhombe ama-demormalities afana namathumbu.

Ukuskena okuhlanganisiwe kwe-tomography (CT)

I-CT Scan isebenzisa ama-X-ray ukudala izithombe ezinemininingwane emzimbeni. Imvamisa umcabango wokuqala ukuzama kusetshenziselwe ukuhlola okusolwayo umdlavuza we-pancreatic. Ukuskena kwe-CT kungasiza ekutholeni usayizi nendawo yesimila, kanye nokuthi kusakazekele yini ezithweni eziseduze noma emithanjeni yegazi.

I-Magnetic Resonance imaging (MRI)

I-MRI isebenzisa amasimu aqinile kazibuthe namagagasi omsakazo ukukhiqiza izithombe ezinemininingwane yomzimba. I-MRI inganikeza izithombe ezinemininingwane eminingi yamanyikwe kanye nezicubu ezizungezile kune-CT Scans, ikakhulukazi lapho ehlola imithambo yegazi ezungeze amanyikwe. Amasu akhethekile we-MRI, njenge-MRCP (i-Magnetic Resonance CholangiopanCreation), gxila kwi-bile kanye ne-pancreatic ducts.

I-endoscopic ultrasound (eus)

I-EUS ihlanganisa i-endoscopy ne-ultrasound ukuhlinzeka ngezithombe eziphezulu ze-pancreas. Ishubhu elincanyana eliguqukayo elinezimo ezinama-ultrasound adluliswa ngomlomo noma u-rectum ungene epheshana lokugaya ukudla. I-EUS ivumela ukubonwa okusondelene kwamanyikwe futhi nakho kungasetshenziselwa ukuthola amasampula wezicubu (ama-biopsies) ukuze kuhlaziywe okunye. Njengochwepheshe ku- I-Shandong Baafa Cancer Research Institute Yazi, lokhu kuhlola kusiza kakhulu.

I-Positron Emission Comography (PET) Scan

I-Pet Scan isebenzisa i-tracer e-radioactive ukuthola izindawo zokwenza umsebenzi we-metabolic emzimbeni, ongakhombisa umdlavuza. Ukuskena kwezilwane zasekhaya kuvame ukuhlanganiswa ne-CT SCANS (PET / CT) ukuhlinzeka ngemininingwane yokusebenza kwe-anatomical nesebenzayo. Ukuskena kwe-Pet / CT kuwusizo ikakhulukazi ekutholeni ukusakazeka kwe umdlavuza we-pancreatic kwezinye izingxenye zomzimba.

Ukuhlolwa Kwegazi

Igazi ukuhlolwa angabona izinto ezithile eziphakanyisiwe kwabanye abantu nge umdlavuza we-pancreatic. Kodwa-ke, igazi ukuhlolwa iyodwa ayinakuxilonga umdlavuza we-pancreatic futhi ngokujwayelekile isetshenziswa ngokubambisana nokucabanga ukuhlolwa.

Ca 19-9

I-CA 19-9 iyisimila esivame ukuphakanyiswa kubantu abane umdlavuza we-pancreatic. Kodwa-ke, futhi kungaphakanyiswa kwezinye izimo, njenge-pancreatitis kanye nokuphazamiseka kwe-bile duct. Ngakho-ke, i-CA 19-9 akuyona ukuhlolwa okuthembekile ukuzama ingomane umdlavuza we-pancreatic, kepha kungasiza ekuqapheleni impendulo yokwelashwa nokuthola kabusha. Ngokusho komphakathi we-American Cancer Society, cishe ama-80% abantu abanayo umdlavuza we-pancreatic ziveze amazinga aphakanyisiwe we-ca 19-9.¹

Isilwane esikhulu

I-Bilirubin yinto ekhiqizwa isibindi. Amazinga aphakeme we-bilirubin egazini angakhombisa ukuqhekeka e-bile duct, engabangelwa yi umdlavuza we-pancreatic. Igazi le-bilirubin ukuzama kuvame ukwenziwa uma umuntu ene-jaundice (kuphuzi kwesikhumba namehlo), uphawu olujwayelekile lwe umdlavuza we-pancreatic.

Izivivinyo Zokusebenza Kwesibindi (LFTS)

Ama-lfts alinganisa amazinga ama-enzyme ahlukahlukene namaprotheni egazini akhiqizwa isibindi. Imiphumela ye-LFT engajwayelekile ingakhombisa ukulimala kwesibindi noma ukulimala, okungabangelwa umdlavuza we-pancreatic Lokho kusakazekele esibindini.

I-Biopsy

I-biopsy ukuphela kwendlela yokuqinisekisa ukuxilongwa kwe umdlavuza we-pancreatic. Ngesikhathi se-biopsy, isampula elincane lezicubu lisuswa kumanyikwe futhi lihlolwe ngaphansi kwesibonakhulu. Ama-biopsies angatholakala ngezindlela ezahlukahlukene, kufaka phakathi:

I-Endoscopic ultrasound-eqondiswa kahle isifiso senaliti (eus-fna)

I-EUS-FNA iyinqubo evusene kakhulu lapho inaliti idluliswa khona odongeni lwesisu noma i-duodenum, iqondiswa yi-ultrasound, ukuthola isampula yezicubu ezivela kumanyikwe.

I-biopsy ye-percutaneous

I-biopsy ephelele ifaka ukufaka inaliti ngesikhumba nasema pansias ukuthola isampula yezicubu. Le nqubo imvamisa yenziwa ngaphansi kwe-CT noma isiqondiso se-ultrasound.

Biopsy yokuhlinzwa

I-biopsy yokuhlinza ifaka ukwenza i-incision esiswini ibone kahle ama-pancreas futhi uthole isampula yezicubu. Le nqubo ivame ukwenziwa lapho ezinye izindlela ze-biopsy zenzeka noma zehlulekile ukunikeza ukuxilongwa.

Ongayilindela ngesikhathi Ukuhlolwa komdlavuza we-pancreatic

Isipiliyoni sokuqhubeka Ukuhlolwa komdlavuza we-pancreatic ingahluka ngokuya ngokuqondile ukuzama kwenziwa. Nakhu umbono ojwayelekile wokuthi yini ongayilindela:

Ngaphambi kokuhlolwa

Udokotela wakho uzohlinzeka ngemiyalo ethile yokuthi ungalungiselela kanjani ngamunye ukuzama. Lokhu kungafaka ukuzila ukudla isikhathi esithile, ukugwema umuthi othile, noma ukuphuza ikhambi elihlukile. Kubalulekile ukulandela le miyalo ngokucophelela ukuqinisekisa ngokunembile ukuzama Imiphumela.

Ngesikhathi sokuhlolwa

Ukucabanga Okuningi ukuhlolwa azinabuhlungu, yize ezinye zingafaka isikhathi esifushane sokungakhululeki noma ukukhathazeka. Ama-biopsies angadala ubuhlungu noma ukungakhululeki, kepha udokotela wakho azohlinzeka ngobuhlakani bendawo ukunciphisa noma yibuphi ubuhlungu. Kubalulekile ukuthi isikhungo senza isivivinyo sihlomele kahle. Ungacabanga ukubheka imininingwane eminingi ngayo I-Shandong Baafa Cancer Research Institute ukuthola izinkomba.

Ngemuva kokuhlolwa

Ngemuva kwe ukuzama, ungathola imiphumela emibi emincane, efana ne-nausea, ukukhathala, noma izinhlungu endaweni ye-biopsy. Le miphumela emibi imvamisa iyisikhashana futhi ixazulule ngokwayo. Udokotela wakho uzohlinzeka ngemiyalo ethile yokuthi ungazinakekela kanjani ngemuva kwe ukuzama nokuthi ungalindela nini imiphumela.

Ukutolika Ukuhlolwa komdlavuza we-pancreatic Umphumela

Ukuhunyushwa kwe Ukuhlolwa komdlavuza we-pancreatic Imiphumela ingaba yinkimbinkimbi futhi idinga ubuchwepheshe bochwepheshe wezempilo ofanelekayo. Kubalulekile ukuxoxa kwakho ukuzama Imiphumela nodokotela wakho ukuqonda ukuthi zisho ukuthini nokuthi yizinyathelo ezilandelayo okufanele zibe yizo.

Ama-Politives angamanga kanye namanga amanga

Kubalulekile ukuthi wazi lokho Ukuhlolwa komdlavuza we-pancreatic azihlali zinembile njalo nge-100%. Imiphumela emihle yamanga (ukuhlolwa ekhombisa umdlavuza lapho ingekho) kanye nemiphumela emibi yamanga (ukuhlolwa Lokho kwehluleka ukuthola umdlavuza lapho kutholakala) kungenzeka.

Ukubaluleka kokulandela

Uma eyakho Ukuhlolwa komdlavuza we-pancreatic Imiphumela ayijwayelekile, udokotela wakho angahle ancome ngokwengeziwe ukuhlolwa ukuqinisekisa noma ukukhipha ukutholwa kwe umdlavuza we-pancreatic. Lokhu kungafaka ukucabanga okwengeziwe ukuhlolwa, biopsies, noma ukubonisana nochwepheshe.

Ikusasa le Ukuhlolwa komdlavuza we-pancreatic

Ucwaningo luyaqhubeka ukuthuthukisa okusha nokunembe kakhudlwana Ukuhlolwa komdlavuza we-pancreatic. Lokhu kufaka phakathi:

• Ama-Biopsies awuketshezi: lezi ukuhlolwa Hlaziya amasampula egazi ukuze ajikeleze amaseli e-tumor noma izicucu ze-DNA ezichithwa amaseli womdlavuza.
• Amasu wokucabanga athuthukisiwe: Abaphenyi bathuthukisa amasu amasha okucabanga angabona amathumbu amancane futhi ahlukanise phakathi kwezilonda ezinobungozi.
• Ukutholwa kwe-Biomarker: Ososayensi basebenzela ukukhomba ama-biomarkers amasha angasetshenziselwa ukuthola umdlavuza we-pancreatic ekuqaleni.

Lolu lwazi luhloselwe ulwazi olujwayelekile kanye nezinhloso zolwazi kuphela, futhi alwenzi izeluleko zezokwelapha. Kubalulekile ukuthintana nochwepheshe wezempilo ofanelekayo nganoma yiziphi izinkathazo zezempilo noma ngaphambi kokwenza noma yiziphi izinqumo ezihlobene nempilo yakho noma yokwelashwa.

1. I-American Cancer Society. (N.D.). Izimpawu nezimpawu zomdlavuza we-pancreatic. Kubuyiselwe kusuka https://www.cancer.org/cancer/types/pancreatic-cancer/detection-diagnosisis-staging/signs-and-symmots.html