Gutanga ibiyobyabwenge byatanzweho Kanseri: Igitabo cyuzuye 

Gutanga ibiyobyabwenge byatanzwe na kanseri nuburyo bwo kuvura bukoresha imiti kurwego rwigifu. Ubu buryo bugamije kuzamura imikorere yo kuvura mugihe tugabanya ingaruka za sisitemu zikunze guhuzwa na chimiotherapi gakondo.

Intangiriro ku itangwa ry'ibiyobyabwenge

Kuvura kanseri gakondo gakondo nka chimiotherapie akenshi birimo ubuyobozi bukoreshwa ibiyobyabwenge, bivuze ko imiti igenda umubiri wose. Mugihe ugira akamaro mukwibanda kuri kanseri, ubu buryo birashobora kandi kugirira nabi ingirabuzimafatizo nziza, biganisha ku ngaruka zikomeye. Gutanga ibiyobyabwenge byahagaritswe itanga uburyo bugamije, gutanga imiti kurubuga.

Ubu buryo burashobora kubamo tekinike zitandukanye, harimo:

• Inshinge zitaziguye ibiyobyabwenge mu kibyimba.
• Gushyira ibiyobyabwenge byorohereza ibiyobyabwenge cyangwa wafers.
• Gukoresha Nanoparticles yagenewe nanoparticles kugirango utange ibiyobyabwenge byumwihariko kuri kanseri.
• Umugati wa chimion, aho ibiyobyabwenge bitangwa ahantu runaka k'umubiri urimo ikibyimba.

Inyungu zo gutanga ibiyobyabwenge

Gutanga ibiyobyabwenge byahagaritswe itanga ibyiza byinshi hejuru yubuvuzi bwa sisitemu:

• Kugabanya ingaruka: Mu kwibanda ku biyobyabwenge kurubuga, guhura nibice bizima bigabanuka, biganisha ku ngaruka nkeya kandi nkeya.
• Kongera ibiyobyabwenge byibasiye ibibyimba: Gutanga kwaho birashobora kugera ku bicuruzwa biri hejuru yibyimba, bishobora guteza imbere imikorere yo kwivuza.
• Kunoza ubuzima bwiza bwo kwihangana: Kugabanya ingaruka no kunoza ibintu byavunjijwe birashobora kuzamura imibereho yumurwayi mugihe cyo kuvura kanseri.
• Ubushobozi bwo kuvura buhuza: Gutanga byaho birashobora guhuzwa nubundi buryo bwo kuvura, nko kubaga, kuvura imirasire, na chimiotherapique ya sisitemu, kugirango igere ku ngaruka za Synergistic.

Tekinike kubitanga byaho

Ubuhanga bwinshi burakoreshwa kuri Gutanga ibiyobyabwenge byahagaritswe, buri kimwe hamwe nibyiza byacyo nuburyo bugarukira:

Inshinge zitaziguye

Ibi birimo gutera imiti mubyigisho. Nuburyo bworoshye kandi ugereranije nuburyo buhebuje bubereye ibibyimba byoroshye. Ubuyobozi bwa ultrasound cyangwa ct burashobora gukoreshwa kugirango habeho neza. Ingero zirimo inshinge za virusi ya oncolytic cyangwa abakozi ba chemitherapeutic.

Kumva ibiyobyabwenge

Ibi bikoresho bisukurwa bikabije cyangwa hafi yikibyimba. Barekura ibiyobyabwenge buhoro buhoro, bitanga ingaruka zikomeje. Gliadel^? WAFER, irimo Carmustine (BCNU), ni urugero ruzwi cyane rwakoreshejwe nyuma yo kubaga ubukana ubwonko.

Nanoparticles

Nanoparticles ni uduce duto rwagenewe gutanga ibiyobyabwenge byumwihariko kuri kanseri. Barashobora kwibasira ibigeragezo byihariye kuri selile za kanseri, bituma ibiyobyabwenge birinda ibibyimba no kugabanya ingaruka zigamije. Liposomes, Polymeric Nanoparticles, na Metal nanoparticles bikunze gukoreshwa.

Chimiotherapi mukarere

Ibi bikubiyemo gutanga ibiyobyabwenge bya chimitherapiri mukarere kamwe k'umubiri birimo ikibyimba. Ingero zirimo:

• Umuhanzi wa Hepatike Corsion (Hai): Ikoreshwa mu kuvura kanseri y'umwijima mu gutanga umuti mu mwijima unyuze mu nzego za hepatike.
• IntraperiTueal chimotherapie (ip): Byakoreshejwe gufata kanseri ya ovarian mugutanga umuti wa chimite mumyanya yinda.
• LIDB yitaruye Perfusion (ILP): Byakoreshejwe gufata melanoma na sarcoma yingingo utandukanya igishushanyo mbonera no gutanga dosiye ndende ya chimiotherapi mu buryo butaziguye.

Ingero zo gutanga ibiyobyabwenge muri kanseri

Gutanga ibiyobyabwenge byahagaritswe ikoreshwa mugufata ubwoko butandukanye bwa kanseri. Dore ingero nke:

Ibibyimba byo mu bwonko

Gliadel^? Wafers iterwa mubwonko nyuma yo kubaga gusubirisha amanota menshi. Ibi wafers birekura Carmustine (BCNU), ibiyobyabwenge bya chimeotherapy, muburyo bwo kubaga, kwica kanseri iyo ari yo yose isigaye. Ubushakashatsi bwasohotse mu kinyamakuru clinical oncology * yerekanye ko gliadel^? wafers inoze cyane kurokoka kubarwayi bafite glioma nyinshi zo murwego rwohejuru.¹

Kanseri y'umwijima

Ihuriro rya Hepatike Umuhanzi (Hai) ni tekinike ya chemotherapy yo mukarere yakoreshwaga kuvura kanseri y'umwijima. Harimo gutanga ibiyobyabwenge bya chimiotherapy mu mwijima unyuze mu nzego za hepatike, intoki nyamukuru yamaraso itanga umwijima. Ibi byemerera kwibanda ku biyobyabwenge kugirango ugere ku kibyimba mugihe ugabanya ingaruka za sisitemu. Ubushakashatsi bwerekanye ko Hai ashobora kunoza kubaho mu barwayi bafite kanseri y'umwijima. Impuguke kuri Shandong Baofa Kanseri Ikigo cyubushakashatsi Koresha cyane ubu buhanga.

Kanseri ya Ovarian

Imitsi yo muri chimotherapial (ip) nubuhanga bwa chemotherapique yakarere bukoreshwa mugufata kanseri ya ovarian. Harimo gutanga ibiyobyabwenge bya chimiotherapy mu cyuho cy'inda, aho kanseri ya ovarian ikwirakwira. Ibi byemerera kwibanda ku biyobyabwenge kugirango ugere kuri selile za kanseri munda. Ubushakashatsi bwerekanye ko IP chimiotherapie ishobora kunoza kubaho mubarwayi bafite kanseri ya terefone yateye imbere.

INGORANE N'UBUYOBOZI BUKURIKIRA

Mugihe Gutanga ibiyobyabwenge byahagaritswe itanga inyungu nyinshi, hariho ibibazo byo gutsinda:

• Ikibyimba Ingirabuzimafatizo za kanseri mu kibyimba zirashobora gutandukana na genese, bikagora kwitiranya selile zose.
• Kurwanya ibiyobyabwenge: Ingirabuzimafatizo za kanseri zirashobora gutsimbataza imiti ya chimitherapie, igabanya imikorere yo gutanga.
• Inzitizi zo gutanga: Ibibyimba bimwe biragoye kubona cyangwa kugira inzitizi zumubiri zibuza ibiyobyabwenge kugera kuri selile zose za kanseri.
• Gukora no kugenzura inzitizi: Gutezimbere no gukora sisitemu yo gutanga ibiyobyabwenge birashobora kugorana kandi bihenze.

Ubushakashatsi buzaza bwibanze ku gukemura ibyo bibazo by:

• Gutezimbere ingamba zifatika zo kwibasira kugirango utsinde ibibyimba.
• Guhuza itangwa ryibiyobyabwenge hamwe nibindi bikoresho, nkibintu mpunorapie na mygeresi, kugirango utsinde ibiyobyabwenge.
• Gutezimbere sisitemu nshya yo gutanga ibiyobyabwenge ishobora kwinjira mubibyimba neza.
• Kurongora ibikorwa byo gukora no kugenzura kuri sisitemu yo gutanga ibiyobyabwenge.

Umwanzuro

Gutanga ibiyobyabwenge byahagaritswe ni uburyo bwo gutanga icyizere bishobora kunoza imikorere yo kuvura no kugabanya ingaruka mbi. Ubwo ubushakashatsi bukomeje, ubu buryo bushobora kugira uruhare rukomeye mu kuvura kanseri. Mugihe cyo kwibasira ibiyobyabwenge kurubuga rwibibyimba, gutanga byaho birashobora gutanga ibyiringiro bishya kubarwayi barwana niyi ndwara yangiza.

Inkoranyamagambo y'amagambo

INGINGO

1. Westphal, M., Hilt, D. C., Bortey, E., Del Mastro, R. F., 习惯, Kizeri, M. (2003). Icyiciro cya 3 Ikigeragezo cya chimiotherapie na carmustine ya biodegrable (BCNU) (Gliadel wafer) kubarwayi bafite glioma yibanze. * Ikinyamakuru cya oncologiya ya kavukire *, * 21 * (24), 4414-4419.