- English
- Chinese
- French
- German
- Portuguese
- Spanish
- Russian
- Japanese
- Korean
- Arabic
- Irish
- Greek
- Turkish
- Italian
- Danish
- Romanian
- Indonesian
- Czech
- Afrikaans
- Swedish
- Polish
- Basque
- Catalan
- Esperanto
- Hindi
- Lao
- Albanian
- Amharic
- Armenian
- Azerbaijani
- Belarusian
- Bengali
- Bosnian
- Bulgarian
- Cebuano
- Chichewa
- Corsican
- Croatian
- Dutch
- Estonian
- Filipino
- Finnish
- Frisian
- Galician
- Georgian
- Gujarati
- Haitian
- Hausa
- Hawaiian
- Hebrew
- Hmong
- Hungarian
- Icelandic
- Igbo
- Javanese
- Kannada
- Kazakh
- Khmer
- Kurdish
- Kyrgyz
- Latin
- Latvian
- Lithuanian
- Luxembou..
- Macedonian
- Malagasy
- Malay
- Malayalam
- Maltese
- Maori
- Marathi
- Mongolian
- Burmese
- Nepali
- Norwegian
- Pashto
- Persian
- Punjabi
- Serbian
- Sesotho
- Sinhala
- Slovak
- Slovenian
- Somali
- Samoan
- Scots Gaelic
- Shona
- Sindhi
- Sundanese
- Swahili
- Tajik
- Tamil
- Telugu
- Thai
- Ukrainian
- Urdu
- Uzbek
- Vietnamese
- Welsh
- Yiddish
- Yoruba
- Zulu
- Kinyarwanda
- Tatar
- Oriya
- Turkmen
- Uyghur
UGqr. Yu BaoofA kunye neqela elivela eUnited States lapapasha inqaku elikwijenali yophando lwe-Gastroenterologron kunye nokuziqhelanisa
2025-02-11
Ugqirha Yu BaofA kunye neqela laseMelika lapapasha ngokudibeneyo inqaku le-autouneeenedines ukuya kwi-turust yomhlaza we-parcreaveranterologron kunye nokuziqhelanisa.
Injongo yolu phando yayikukuvavanya ukubaluleka kweklinikhi ye-autououneounedies kwi-GNA11, i-MSLN, GNS, CEBPA, i-CEBM2, PNMO, i-MDM2, Pten, iPin kwi-panncreatic umhlaza (PC). Zizonke iisampulu ezingama-33 ze-Serum ezivela kwizigulana zePC kunye neesampulu ezingama-45 ze-Serum ezivela kulawulo oluqhelekileyo (NC) zibandakanyiwe, kwaye iindidi ezili-9 ze-Autusousounegines zifunyanwe i-Enzyme Assay Assay (Elisa). Vavanya usebenzisa iiparamitha ezininzi kwifom okanye kwifom edibeneyo. Ngaphandle kwe-Anti Gnas kunye neCalnic Calnuc, amanqanaba onke amanye amanye ama-arauntainedines aphezulu kakhulu kunaleyo ikwiqela eliqhelekileyo lolawulo. Xa kuthelekiswa neqela eliqhelekileyo lolawulo (i-4.9%), amasango amane aaseeenedines, i-MSLN, pten, i-proe1, i-75.8%, i-30.3%, ngokwahlukeneyo. Amandla ale auredabodies ukwahlula indawo ephantsi kwe-roc curve (i-Auc) ukusuka kwi-0.666 ukuya kwi-0.666 ukuya kwi-0.666 ukuya kwi-0.666 ukuya kwi-0.666 ukuya kwi-0.884, i-Anti-P16 Indibaniselwano ka-Anti-msln kunye ne-anti-p16 inokuphucula ubuntununtunu bokuxilongwa.
Ukongeza, zombini i-MSLN kunye ne-Sui1 AUAUTEGOAGECEMOS inciphile kwizigulana emva kwe-chemotherapy. Ii-araunties ezine ezichasene ne-MSLN, p16, uSui1 kunye nePten babonisa ababukeli abanokubakho kwi-pancreastic yomhlaza we-pancreatic yomhlaza we-pancreatic, apho i-anti msln kunye ne-Anti P16 yayiyeyona ilungileyo. Ukudityaniswa kwezi zinto zimbini ze-auradabounedines kubonisa ezona zinto zibalulekileyo kwezoqoqosho kunye nempumelelo. Ukubaluleka kokuhla kwe-areantiboinedies nxamnye ne-MSLN kunye neSUI1 kwizigulana ze-PC emva kokuba i-chemotherapy ifuna ukuphononongwa kwakhona.
Uphando malunga ne-aumor acturesphenedines lubonelela ngokubhekisele kwireferensi ebalulekileyo ekuhlolweni kwangoko, isifo, kunye nonyango lwamathumba. I-ICACOOPIC YU BUOFA ifake i-tumor aauntibodies kwi-Tumor Unyango olungaphezulu kweminyaka engama-20 eyadlulayo.
